Structure and conformational analysis of the anti-HIV reverse transcriptase inhibitor AZT using MP2 and DFT methods. Differences with the natural nucleoside thymidine. Simulation of the 1st phosphorylation step with ATP
2014 ◽
Vol 16
(45)
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pp. 24763-24783
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Keyword(s):
Anti Hiv
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A proton-transfer mechanism is proposed for the first phosphorylation step of the nucleoside HIV-1 reverse transcriptase inhibitor AZT (3′-azido-3′ deoxythymidine) by interacting with ATP.
2014 ◽
Vol 21
(7)
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pp. 925-935
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2011 ◽
Vol 22
(2)
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pp. 57-65
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1995 ◽
Vol 6
(6)
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pp. 365-370
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2001 ◽
Vol 61
(12)
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pp. 1531-1535
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2012 ◽
2008 ◽
Vol 18
(3)
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pp. 1120-1123
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2007 ◽
Vol 22
(5)
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pp. 591-607
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