Mechanochemical milling promoted solvent-free imino Diels–Alder reaction catalyzed by FeCl3: diastereoselective synthesis of cis-2,4-diphenyl-1,2,3,4-tetrahydroquinolines

RSC Advances ◽  
2014 ◽  
Vol 4 (67) ◽  
pp. 35635-35638 ◽  
Author(s):  
Ya-Jun Tan ◽  
Ze Zhang ◽  
Fang-Jian Wang ◽  
Hao-Hao Wu ◽  
Qing-Hai Li
Keyword(s):  
Ball Milling ◽  
Alder Reaction ◽  
Diels Alder ◽  
Solvent Free ◽  
Diastereoselective Synthesis ◽  
Diels Alder Reaction ◽  
Mechanochemical Milling

Cis-2,4-diphenyl-1,2,3,4-tetrahydroquinolines were diastereoselectively synthesized by FeCl3-promoted solvent-free Diels–Alder reaction of in situ generated imine with styrene under ball milling.

Diastereoselective Synthesis of Functionalized Tetrahydropyridazines Containing Indole Scaffolds via Inverse-Electron-Demand Aza-Diels–Alder Reaction

2021 ◽  
Author(s):  
Taotao Chen ◽  
Chao Che ◽  
Zhefei Guo ◽  
Xiu-Qin Dong ◽  
Chun-Jiang Wang
Keyword(s):  
Alder Reaction ◽  
Diels Alder ◽  
Diastereoselective Synthesis ◽  
Inverse Electron Demand ◽  
Catalyst Free ◽  
Diels Alder Reaction ◽  
Electron Demand

An unprecedented base-promoted and catalyst-free inverse-electron-demand aza-Diels-Alder (IEDDA) reaction between the easily available in situ generated azoalkenes and 3-vinylindoles has been developed. This efficient protocol afforded structurally important tetrahydropyridazines containing...

Preparation of graphene via wet ball milling and in situ reversible modification with the Diels–Alder reaction

2020 ◽  
Vol 44 (4) ◽  
pp. 1236-1244 ◽  
Author(s):  
Jianfeng Xu ◽  
Xiaomin Zhao ◽  
Feixiang Liu ◽  
Lun Jin ◽  
Guohua Chen
Keyword(s):  
Ball Milling ◽  
Alder Reaction ◽  
Diels Alder ◽  
Functionalized Graphene ◽  
Diels Alder Reaction ◽  
Reversible Modification

Functionalized graphene (G-MA) was prepared by a facile wet ball milling strategy, which achieved exfoliation and functionalization of graphite simultaneously.

scholarly journals Diastereoselective synthesis of novel spiro indanone fused pyrano[3,2-c]chromene derivatives following hetero-Diels–Alder reaction andin vitroanticancer studies

RSC Advances ◽  
2018 ◽  
Vol 8 (30) ◽  
pp. 16802-16814 ◽  
Author(s):  
Pravati Panda ◽  
Sabita Nayak ◽  
Susanta Ku. Sahoo ◽  
Seetaram Mohapatra ◽  
Deepika Nayak ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Alder Reaction ◽  
Diels Alder ◽  
Diastereoselective Synthesis ◽  
Diels Alder Reaction

Synthesis of novel spiro indanone fused pyrano[3,2-c]chromene derivatives following hetero-Diels–Alder reaction has been demonstrated and evaluated for theirin vitroanticancer activity.

Organocatalytic enantioselective Diels–Alder reaction between hydroxymaleimides and in situ generated nitrosoalkenes for direct preparation of chiral hemiketals with 1,2-oxazine skeleton

2021 ◽  
Author(s):  
Min Xiang ◽  
Chen-Yi Li ◽  
Jian Zhang ◽  
Ying Zou ◽  
Wen-Sheng Li ◽  
...  
Keyword(s):  
Alder Reaction ◽  
Diels Alder ◽  
Diels Alder Reaction ◽  
Direct Preparation

Organocatalytic Enantioselective IEDDA reaction between hydroxymaleimides and in situ generated nitrosoalkenes has been disclosed, a series of chiral hemiketals containing 5,6-dihydro-4H-l,2-oxazines and succinimide frameworks have been prepared.

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