Sequential Au(i)/chiral tertiary amine catalysis: a tandem C–H functionalization of anisoles or a thiophene/asymmetric Michael addition sequence to quaternary oxindoles

2016 ◽  
Vol 52 (12) ◽  
pp. 2537-2540 ◽  
Author(s):  
Zhong-Yan Cao ◽  
Yu-Lei Zhao ◽  
Jian Zhou
Keyword(s):  
Tertiary Amine ◽  
Michael Addition ◽  
Enantioselective Synthesis ◽  
Asymmetric Michael Addition ◽  
Amine Catalysis

We report an unprecedented sequential Au(i)/bifunctional tertiary amine catalysis, which enables a tandem C–H functionalization of weak nucleophiles (anisoles or thiophenes) and asymmetric Michael addition for the highly enantioselective synthesis of quaternary oxindoles.

ChemInform Abstract: Highly Enantioselective Synthesis of α-Fluoro-α-nitro Esters via Organocatalyzed Asymmetric Michael Addition.

ChemInform ◽  
2011 ◽  
Vol 42 (16) ◽  
pp. no-no
Author(s):  
Hai-Feng Cui ◽  
Peng Li ◽  
Xiao-Wei Wang ◽  
Zhuo Chai ◽  
Ying-Quan Yang ◽  
...  
Keyword(s):  
Michael Addition ◽  
Enantioselective Synthesis ◽  
Asymmetric Michael Addition ◽  
Nitro Esters

Asymmetric Michael addition between kojic acid derivatives and unsaturated ketoesters promoted by C2-symmetric organocatalysts

2018 ◽  
Vol 16 (48) ◽  
pp. 9314-9318 ◽  
Author(s):  
Alexey A. Kostenko ◽  
Alexander S. Kucherenko ◽  
Andrey N. Komogortsev ◽  
Boris V. Lichitsky ◽  
Sergei G. Zlotin
Keyword(s):  
Tertiary Amine ◽  
Michael Addition ◽  
Kojic Acid ◽  
Domino Reaction ◽  
Asymmetric Michael Addition

An efficient C2-symmetric bifunctional tertiary amine–squaramide organocatalyst for the asymmetric Michael addition/hemiketalization domino reaction of kojic acid derivatives with β,γ-unsaturated α-ketoesters has been designed.

Asymmetric Michael Addition of α-Substituted Isocyanoacetates with Maleimides Catalyzed by Chiral Tertiary Amine Thiourea

2012 ◽  
Vol 77 (6) ◽  
pp. 2947-2953 ◽  
Author(s):  
Jian-Fei Bai ◽  
Liang-Liang Wang ◽  
Lin Peng ◽  
Yun-Long Guo ◽  
Li-Na Jia ◽  
...  
Keyword(s):  
Tertiary Amine ◽  
Michael Addition ◽  
Asymmetric Michael Addition
Sign in / Sign up

Export Citation Format

Share Document