Rhodium-mediated asymmetric transfer hydrogenation: a diastereo- and enantioselective synthesis of syn-α-amido β-hydroxy esters

The use of a Rh- instead of a Ru-complex in the asymmetric transfer hydrogenation of α-benzoylamino β-keto esters allowed a reversal of diastereoselectivity and an efficient access to a variety of syn α-amido β-hydroxy esters.

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ChemInform Abstract: Enantioselective Synthesis of anti-β-Amido-α-hydroxy Esters via Asymmetric Transfer Hydrogenation Coupled with Dynamic Kinetic Resolution.

ChemInform ◽

10.1002/chin.201402050 ◽

2013 ◽

Vol 45 (2) ◽

pp. no-no

Author(s):

Marvin Villacrez ◽

Peter Somfai

Keyword(s):

Kinetic Resolution ◽

Enantioselective Synthesis ◽

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation ◽

Dynamic Kinetic Resolution ◽

Hydroxy Esters

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A rapid and green approach to chiral α-hydroxy esters: asymmetric transfer hydrogenation (ATH) of α-keto esters in water by use of surfactants

Tetrahedron Asymmetry ◽

10.1016/j.tetasy.2009.08.019 ◽

2009 ◽

Vol 20 (17) ◽

pp. 2033-2037 ◽

Cited By ~ 22

Author(s):

Lu Yin ◽

Xian Jia ◽

Xingshu Li ◽

Albert S.C. Chan

Keyword(s):

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation ◽

Keto Esters ◽

Green Approach ◽

Hydroxy Esters

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ChemInform Abstract: A Rapid and Green Approach to Chiral α-Hydroxy Esters: Asymmetric Transfer Hydrogenation (ATH) of α-Keto Esters in Water by Use of Surfactants.

ChemInform ◽

10.1002/chin.201008073 ◽

2010 ◽

Vol 41 (8) ◽

Author(s):

Lu Yin ◽

Xian Jia ◽

Xingshu Li ◽

Albert S. C. Chan

Keyword(s):

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation ◽

Keto Esters ◽

Green Approach ◽

Hydroxy Esters

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Enantioselective synthesis of anti-β-amido-α-hydroxy esters via asymmetric transfer hydrogenation coupled with dynamic kinetic resolution

Tetrahedron Letters ◽

10.1016/j.tetlet.2013.07.100 ◽

2013 ◽

Vol 54 (38) ◽

pp. 5266-5268 ◽

Cited By ~ 14

Author(s):

Marvin Villacrez ◽

Peter Somfai

Keyword(s):

Kinetic Resolution ◽

Enantioselective Synthesis ◽

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation ◽

Dynamic Kinetic Resolution ◽

Hydroxy Esters

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Enantioselective Synthesis of 1-Aryl-Substituted Tetrahydroisoquinolines Through Ru-Catalyzed Asymmetric Transfer Hydrogenation

European Journal of Organic Chemistry ◽

10.1002/ejoc.201500951 ◽

2015 ◽

Vol 2015 (29) ◽

pp. 6503-6514 ◽

Cited By ~ 17

Author(s):

Marc Perez ◽

Zi Wu ◽

Michelangelo Scalone ◽

Tahar Ayad ◽

Virginie Ratovelomanana-Vidal

Keyword(s):

Enantioselective Synthesis ◽

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation

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Enantioselective Synthesis of (S)-γ-Amino Alcohols by Ru/Rh/Ir Catalyzed Asymmetric Transfer Hydrogenation (ATH) with Tunable Chiral Tetraaza Ligands in Water

Catalysis Letters ◽

10.1007/s10562-018-2641-8 ◽

2019 ◽

Vol 149 (2) ◽

pp. 601-609 ◽

Cited By ~ 4

Author(s):

Jianxiang Chen ◽

Tian Zhang ◽

Xungao Liu ◽

Liang Shen

Keyword(s):

Amino Alcohols ◽

Enantioselective Synthesis ◽

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation

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Corrigendum to “Enantioselective synthesis of β-hydroxy amines and aziridines using asymmetric transfer hydrogenation of α-amido ketones”

Tetrahedron Asymmetry ◽

10.1016/s0957-4166(01)00154-9 ◽

2001 ◽

Vol 12 (6) ◽

pp. 965

Author(s):

Aparecida M. Kawamoto ◽

Martin Wills

Keyword(s):

Enantioselective Synthesis ◽

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation

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Efficient access to chiral benzo[c]chromenes via asymmetric transfer hydrogenation of ketals

Organic Chemistry Frontiers ◽

10.1039/c8qo00096d ◽

2018 ◽

Vol 5 (8) ◽

pp. 1280-1283 ◽

Cited By ~ 2

Author(s):

Yangshan Li ◽

Miao Wan ◽

Shutao Sun ◽

Zhongjun Fu ◽

Haofei Huang ◽

...

Keyword(s):

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation ◽

Efficient Access ◽

Acid Catalyzed

A highly enantioselective method to chiral α-substituted 6H-benzo[c]chromenes through chiral imidodiphosphoric acid-catalyzed asymmetric transfer hydrogenation of ketals has been established.

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