scholarly journals Conversion of N-acyl amidines to amidoximes: a convenient synthetic approach to molnupiravir (EIDD-2801) from ribose

RSC Advances ◽  
2021 ◽  
Vol 11 (57) ◽  
pp. 36143-36147
Author(s):  
Ajaz Ahmed ◽  
Qazi Naveed Ahmed ◽  
Debaraj Mukherjee
Keyword(s):  
Synthetic Approach ◽  
Stereoselective Glycosylation ◽  
Convenient Synthetic Approach

A method for the preparation of molnupiravir (EIDD-2801) via regioselective conversion of an N-acyl-nucleoside intermediate, generated through stereoselective glycosylation of protected ribose and N4-acetyl cytosine, to an amidoxime.

scholarly journals α-(Imino)pyridyldifluoroethyl Phosphonates: Novel Promising Building Blocks in Synthesis of Biorelevant Aminophosphonic Acids Derivatives

Organics ◽  
2021 ◽  
Vol 2 (2) ◽  
pp. 72-83
Author(s):  
Oksana M. Shavrina ◽  
Lyudmyla V. Bezgubenko ◽  
Andrii V. Bezdudny ◽  
Petro P. Onys’ko ◽  
Yuliya V. Rassukana
Keyword(s):  
Carbon Atom ◽  
Building Blocks ◽  
Synthetic Approach ◽  
Phosphonic Acids ◽  
Aminophosphonic Acids ◽  
Convenient Synthetic Approach

A convenient synthetic approach to previously unknown NH-iminophosphonates bearing 2-, 3-, and 4-pyridyldifluoromethyl groups at the imine carbon atom was developed. The synthetic potential of these novel building blocks was demonstrated by their conversion into highly functionalized acyclic and heterocyclic aminophosphonates and phosphonic acids combining in their structure biorelevant aminophosphonic fragment, difluoromethyl group, and pyridyl, piperidyl, thiazolidin-4-one, or thiazidinan-4-one heterocyclic moieties in a single molecular platform.

Convenient synthetic approach towards high alcohol esters of 5-aryl-2,2′-bipyridine-5′-carboxylic acids

2020 ◽  
Author(s):  
Dmitry S. Kopchuk ◽  
Ekaterina S. Starnovskaya ◽  
Yaroslav K. Shtaitz ◽  
Maria I. Savchuk ◽  
Alexey P. Krinochkin ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Synthetic Approach ◽  
High Alcohol ◽  
Convenient Synthetic Approach

Convenient Synthetic Approach to 2,4-Disubstituted Quinazolines

2007 ◽  
Vol 9 (1) ◽  
pp. 69-72 ◽  
Author(s):  
Serena Ferrini ◽  
Fabio Ponticelli ◽  
Maurizio Taddei
Keyword(s):  
Synthetic Approach ◽  
Convenient Synthetic Approach

scholarly journals Convenient Synthetic Approach to 2,4-Disubstituted Quinazolines.

ChemInform ◽  
2007 ◽  
Vol 38 (20) ◽  
Author(s):  
Serena Ferrini ◽  
Fabio Ponticelli ◽  
Maurizio Taddei
Keyword(s):  
Synthetic Approach ◽  
Convenient Synthetic Approach

A convenient synthetic approach to alpha-amino-beta-lactam synthesis promoted by phenyl dichlorophosphate reagent

1984 ◽  
Vol 25 (35) ◽  
pp. 3905-3908 ◽  
Author(s):  
Jesus M. Aizpurua ◽  
Inlaki Ganboa ◽  
Fernando P. Cossío ◽  
Alberto Gonzalez ◽  
Ana Arrieta ◽  
...  
Keyword(s):  
Synthetic Approach ◽  
Beta Lactam ◽  
Convenient Synthetic Approach

A new convenient synthetic approach to diarylpyrimidines

Tetrahedron ◽  
2016 ◽  
Vol 72 (27-28) ◽  
pp. 3922-3929 ◽  
Author(s):  
Antonio Guirado ◽  
Enrique Alarcón ◽  
Yesica Vicente ◽  
Raquel Andreu ◽  
Delia Bautista ◽  
...  
Keyword(s):  
Synthetic Approach ◽  
Convenient Synthetic Approach

scholarly journals A Convenient Synthetic Approach to 4-Substituted Indoles

Heterocycles ◽  
1987 ◽  
Vol 26 (5) ◽  
pp. 1173 ◽  
Author(s):  
Masanori Somei ◽  
Fumio Yamada
Keyword(s):  
Synthetic Approach ◽  
Convenient Synthetic Approach
Sign in / Sign up

Export Citation Format

Share Document