Relationship between Arterial Blood Pressure and Dietary Sodium Intake in Essential Hypertension and in Normotensive Subjects

1981 ◽  
Vol 60 (3) ◽  
pp. 7P-7P
Author(s):  
P. S. Parfrey ◽  
N. D. Markandu ◽  
J. E. Roulston ◽  
B. E. Jones ◽  
G. A. MacGregor
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Arterial Blood Pressure ◽  
Sodium Intake ◽  
Dietary Sodium ◽  
Arterial Blood ◽  
Normotensive Subjects

Relationship between Arterial Blood Pressure and Dietary Sodium Intake in Subjects with and without a Familial Predisposition to Hypertension

1981 ◽  
Vol 61 (3) ◽  
pp. 30P-30P
Author(s):  
P.S. Parfrey ◽  
C.R. Lee ◽  
N.D. Markandu ◽  
J.E. Roulston ◽  
M. Squires ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Sodium Intake ◽  
Dietary Sodium ◽  
Familial Predisposition ◽  
Arterial Blood

Plasma Noradrenaline and the Pressor Action of Exogenous Noradrenaline in Normotensive Subjects and Patients with Essential Hypertension

1978 ◽  
Vol 55 (s4) ◽  
pp. 61s-63s ◽  
Author(s):  
T. Philipp ◽  
A. Distler ◽  
U. Cordes ◽  
H. P. Wolff
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Arterial Blood Pressure ◽  
Inverse Relationship ◽  
Pressor Response ◽  
Blood Pressure Level ◽  
Plasma Noradrenaline ◽  
Arterial Blood ◽  
Adrenergic Activity ◽  
Normotensive Subjects

1. An inverse relationship was found between plasma noradrenaline and reactivity to exogenous noradrenaline in normotensive subjects. 2. The relationship between plasma noradrenaline and reactivity was disturbed in age-matched patients with essential hypertension. 3. A multiple-regression analysis showed a highly significant correlation between adrenergic activity and reactivity to noradrenaline and the mean arterial blood pressure level (r = 0·91). The results suggest that adrenergic activity and pressor response to noradrenaline combined are important determinants of arterial blood pressure. 4. An inverse relationship could also be demonstrated between plasma renin activity and reactivity to exogenous angiotensin II. No difference was observed between normotensive and hypertensive subjects.

Influence of arterial blood pressure and aldosterone on left ventricular hypertrophy in moderate essential hypertension

1993 ◽  
Vol 71 (3) ◽  
pp. A17-A20 ◽  
Author(s):  
Daniel A. Duprez ◽  
Frank R. Bauwens ◽  
Marc L. De Buyzere ◽  
Tine L. De Backer ◽  
Jean M. Kaufman ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Left Ventricular Hypertrophy ◽  
Arterial Blood Pressure ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Moderate Essential Hypertension ◽  
Arterial Blood

Assessment of the Antihypertensive Effect of Atenolol with 24 H Ambulatory Monitoring of Blood Pressure

1979 ◽  
Vol 57 (s5) ◽  
pp. 387s-389s ◽  
Author(s):  
J. S. Floras ◽  
P. Fox ◽  
M. O. Hassan ◽  
J. V. Jones ◽  
P. Sleight ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Arterial Blood Pressure ◽  
Antihypertensive Effect ◽  
Ambulatory Monitoring ◽  
Single Daily Dose ◽  
Pressure Measurements ◽  
Arterial Blood ◽  
Blood Pressure Study ◽  
Daily Dose

1. Twenty-four hour intra-arterial blood pressure measurements and electrocardiograms were obtained from 12 subjects with untreated essential hypertension. 2. The patients kept records of their activity, paying particular attention to times of retiring to bed, and times of waking in the morning. 3. All subjects were treated with a single daily dose of atenolol (50 to 200 mg) for between 2 and 9 months, and then underwent a second 24 h blood pressure study. 4. Arterial blood pressure was lowered significantly throughout the 24 h period with a single daily dose of atenolol.

Solitary Kidney and Ageing as Causes of Low Renin and Aldosterone Concentrations: Relevance to ‘Low-Renin’ Essential Hypertension

1976 ◽  
Vol 51 (s3) ◽  
pp. 177s-180s ◽  
Author(s):  
R. Gordon ◽  
Freda Doran ◽  
M. Thomas ◽  
Frances Thomas ◽  
P. Cheras
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Plasma Renin Activity ◽  
Plasma Volume ◽  
Plasma Renin ◽  
Renin Activity ◽  
Dietary Sodium ◽  
Sodium Restriction ◽  
Normotensive Subjects ◽  
The Mean

1. As experimental models of reduced nephron population in man, (a) twelve men aged 15–32 years who had one kidney removed 1–13 years previously and (b) fourteen normotensive men aged 70–90 years were studied. Results were compared with those in eighteen normotensive men aged 18–28 years and eleven men aged 19–33 years with essential hypertension. 2. While the subjects followed a routine of normal diet and daily activity, measurements were made, after overnight recumbency and in the fasting state, of plasma volume and renin activity on one occasion in hospital and of blood pressure on five to fourteen occasions in the home. Blood pressure was also measured after standing for 2 min and plasma renin activity after 1 h standing, sitting or walking. Twenty-four hour urinary aldosterone excretion was also measured. 3. The measurements were repeated in the normotensive subjects and subjects in (a) and (b) above after 10 days of sodium-restricted diet (40 mmol of sodium/day). 4. The mean plasma renin activity (recumbent) in essential hypertensive subjects was higher than in normotensive subjects. In subjects of (a) and (b) above, it was lower than normotensive subjects, and was not increased by dietary sodium restriction in subjects of (a). 5. The mean aldosterone excretion level was lower in old normotensive subjects than in the other groups, and increased in each group after dietary sodium restriction. 6. Mean plasma volume/surface area was not different between the four groups and in normotensive, essential hypertensive and nephrectomized subjects but not subjects aged 70–90 years was negatively correlated with standing diastolic blood pressure.

scholarly journals Comparative Effects of Prazosin and Phenoxybenzamine on Arterial Blood Pressure, Heart Rate, and Plasma Catecholamines in Essential Hypertension

1979 ◽  
Vol 1 ◽  
pp. S1-7 ◽  
Author(s):  
Julia Mulvihill-Wilson ◽  
Robert M. Graham ◽  
William Pettinger ◽  
Carolyn Muckleroy ◽  
Shirley Anderson ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Essential Hypertension ◽  
Arterial Blood Pressure ◽  
Plasma Catecholamines ◽  
Arterial Blood

Naloxone enhances the increase in plasma growth hormone induced by α2-adrenergic stimulation in healthy males

1987 ◽  
Vol 114 (2) ◽  
pp. 308-313 ◽  
Author(s):  
Margareta Bramnert ◽  
Bernt Hökfelt
Keyword(s):  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Adrenergic Stimulation ◽  
Arterial Blood ◽  
Normotensive Subjects ◽  
Pre Treatment ◽  
Plasma Gh ◽  
Single Blind ◽  
Healthy Males

Abstract. There is evidence that the α2-adrenergic agonist clonidine interacts with the opioid system. In the present investigations, the effect of naloxone on the increase in plasma GH induced by clonidine and the more specific α2-agonist guanfacine was studied in man. In a single-blind study, five healthy males received in randomized order either the preservatives in the naloxone preparation (control) or naloxone at two different doses (10 or 100 μg/kg) followed by an infusion of either diluted preservatives or naloxone (5 or 50 μg · kg−1 · h−1, respectively). Fifteen min after the bolus dose, clonidine (3 μg/kg) or guanfacine (15 μg/kg) was infused over 10 min in a single-blind order. Both clonidine and guanfacine induced an increase in plasma GH (P < 0.05), Pre-treatment with naloxone at the higher dosage resulted in an enhanced (P < 0.05) GH response to clonidine and guanfacine, respectively, whereas the lower dosage of naloxone was without effect. The increase in plasma GH did not correlate with basal mean arterial blood pressure, nor with the changes in mean arterial blood pressure induced by clonidine or guanfacine. These results indicate that the increase in plasma GH induced by α2-adrenergic stimulation in normotensive subjects involves opioid receptors with moderate sensitivity to naloxone.

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