Effects of a thromboxane receptor antagonist (NT-126) and a thromboxane synthase inhibitor (OKY-O46) on protamine-induced circulatory changes in dogs

Taro Mizutani; Shinji Takahashi; Shin-ichi Kihara; Hidenori Toyooka

doi:10.1053/jcan.2000.18449

Effects of a thromboxane receptor antagonist (NT-126) and a thromboxane synthase inhibitor (OKY-O46) on protamine-induced circulatory changes in dogs

Journal of Cardiothoracic and Vascular Anesthesia ◽

10.1053/jcan.2000.18449 ◽

2000 ◽

Vol 14 (6) ◽

pp. 687-692 ◽

Cited By ~ 4

Author(s):

Taro Mizutani ◽

Shinji Takahashi ◽

Shin-ichi Kihara ◽

Hidenori Toyooka

Keyword(s):

Receptor Antagonist ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

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In Vitro and in Vivo Pharmacological Characterization of BM-613 [N-n-Pentyl-N′-[2-(4′-methylphenylamino)-5-nitrobenzenesulfonyl]urea], a Novel Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.104.079301 ◽

2004 ◽

Vol 313 (1) ◽

pp. 293-301 ◽

Cited By ~ 10

Author(s):

Julien Hanson ◽

Stephanie Rolin ◽

Denis Reynaud ◽

Na Qiao ◽

Leanne P. Kelley ◽

...

Keyword(s):

Receptor Antagonist ◽

Pharmacological Characterization ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

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The dual thromboxane receptor antagonist and thromboxane synthase inhibitor EV-077 is a more potent inhibitor of platelet function than aspirin

Journal of Thrombosis and Haemostasis ◽

10.1111/j.1538-7836.2011.04446.x ◽

2011 ◽

Vol 9 (10) ◽

pp. 2109-2111 ◽

Cited By ~ 15

Author(s):

P. FONTANA ◽

P. ALBERTS ◽

K. S. SAKARIASSEN ◽

H. BOUNAMEAUX ◽

J.-P. MEYER ◽

...

Keyword(s):

Receptor Antagonist ◽

Platelet Function ◽

Potent Inhibitor ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

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Basic pharmacophore of some antithrombotic agents with combined thromboxane receptor antagonist (TxRA)/thromboxane synthase inhibitor (TxSI) activity

Drug Development Research ◽

10.1002/(sici)1098-2299(199610)39:2<197::aid-ddr14>3.0.co;2-9 ◽

1996 ◽

Vol 39 (2) ◽

pp. 197-200 ◽

Cited By ~ 3

Author(s):

Yang Jie ◽

Hua Weiyi

Keyword(s):

Receptor Antagonist ◽

Antithrombotic Agents ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

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Oxa-prostanoid analogs. Identification of an orally effective, dual thromboxane receptor antagonist /thromboxane synthase inhibitor

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(01)80104-9 ◽

1994 ◽

Vol 4 (17) ◽

pp. 2073-2076 ◽

Cited By ~ 2

Author(s):

I. Vlattas ◽

J. Dellureficio ◽

D.S. Cohen ◽

W. Lee ◽

F. Clarke ◽

...

Keyword(s):

Receptor Antagonist ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

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Pharmacology of the Thromboxane Receptor Antagonist and Thromboxane Synthase Inhibitor BM-531

Cardiovascular Drug Reviews ◽

10.1111/j.1527-3466.2001.tb00057.x ◽

2006 ◽

Vol 19 (2) ◽

pp. 87-96 ◽

Cited By ~ 21

Author(s):

Jean-Michel Dogné ◽

Stéphanie Rolin ◽

Xavier Leval ◽

Patricia Benoit ◽

Philippe Neven ◽

...

Keyword(s):

Receptor Antagonist ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

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Thia-prostanoid analogs with combined thromboxane receptor antagonist/thromboxane synthase inhibitor activities. Synthesis and pharmacological evaluation

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(01)80103-7 ◽

1994 ◽

Vol 4 (17) ◽

pp. 2067-2072 ◽

Cited By ~ 2

Author(s):

I. Vlattas ◽

J. Dellureficio ◽

D.S. Cohen ◽

W. Lee ◽

F. Clarke ◽

...

Keyword(s):

Receptor Antagonist ◽

Thromboxane Synthase ◽

Pharmacological Evaluation ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

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Novel antithrombotic agents with combined thromboxane receptor antagonist (TxRA)/thromboxane synthase inhibitor (TxSI) activities

Drugs of the Future ◽

10.1358/dof.1994.019.08.595795 ◽

1994 ◽

Vol 19 (8) ◽

pp. 765 ◽

Cited By ~ 9

Author(s):

S.S. Bhagwat

Keyword(s):

Receptor Antagonist ◽

Antithrombotic Agents ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

Download Full-text

BM-573, a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, Prevents Pig Myocardial Infarction Induced by Coronary Thrombosis

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.102.046607 ◽

2003 ◽

Vol 306 (1) ◽

pp. 59-65 ◽

Cited By ~ 20

Author(s):

S. Rolin ◽

M. Petein ◽

V. Tchana-Sato ◽

J. M. Dogne ◽

P. Benoit ◽

...

Keyword(s):

Myocardial Infarction ◽

Receptor Antagonist ◽

Coronary Thrombosis ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

Download Full-text

ChemInform Abstract: Oxa-Prostanoid Analogues. Identification of an Orally Effective, Dual Thromboxane Receptor Antagonist (TxRA)/Thromboxane Synthase Inhibitor.

ChemInform ◽

10.1002/chin.199510281 ◽

2010 ◽

Vol 26 (10) ◽

pp. no-no

Author(s):

I. VLATTAS ◽

J. DELLUREFICIO ◽

D. S. COHEN ◽

W. LEE ◽

F. CLARKE ◽

...

Keyword(s):

Receptor Antagonist ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

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Effect of DT-TX 30, a Combined Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, on Retinal Vascularity in Experimental Diabetes Mellitus

Thrombosis Research ◽

10.1016/s0049-3848(99)00173-5 ◽

2000 ◽

Vol 97 (3) ◽

pp. 125-131 ◽

Cited By ~ 12

Author(s):

José P. De La Cruz ◽

Antonio Moreno ◽

Marı́a I. Ruiz-Ruiz ◽

Felipe Sánchez De La Cuesta

Keyword(s):

Diabetes Mellitus ◽

Receptor Antagonist ◽

Experimental Diabetes ◽

Experimental Diabetes Mellitus ◽

Thromboxane Synthase ◽

Thromboxane Receptor ◽

Thromboxane Synthase Inhibitor ◽

Thromboxane Receptor Antagonist ◽

Synthase Inhibitor

Download Full-text