Formation, Viscosity and Degradation of Artificial Thrombi after Cadaveric-Donor Kidney Transplantation

1971 ◽  
Vol 26 (01) ◽  
pp. 029-037
Author(s):  
L Dintenfass ◽  
J. H Stewart

SummaryDynamic (VFTV) coagulation and thrombus formation studies were carried out on 15 patients who had undergone cadaveric-donor kidney transplantation and 6 patients with end-stage renal failure awaiting transplantation.All patients whose kidney graft functioned successfully and without major medical complications showed a coagulation VFTV pattern similar to that of healthy normals. This pattern was present as early as 1 week after transplantation.Abnormal VFTV pattern (i.a., greatly elevated viscosity), characterised patients awaiting transplantation (6 patients) and 4 patients with serious medical complications following transplantation.Viscosities of thrombi were two and a half to three-fold higher, and rates of thrombus degradation two to ten fold higher, in the complicated than in the successful kidney transplants.The viscosity increase is not counteracted by haemodialysis or immunosuppressive drugs.The difference of VFTV parameters between patients awaiting transplantation and normals and between complicated transplant patients and normals were significant to p <0.005 and p <0.001 respectively.

2019 ◽  
Vol 8 (7) ◽  
pp. 955 ◽  
Author(s):  
Jin Go ◽  
Sun-Cheol Park ◽  
Sang-Seob Yun ◽  
Jiyeon Ku ◽  
Jaesik Park ◽  
...  

The effects of hyperchloremia on kidney grafts have not been investigated in patients undergoing living-donor kidney transplantation (LDKT). In this study, data from 200 adult patients undergoing elective LDKT between January 2016 and December 2017 were analyzed after propensity score (PS) matching. The patients were allocated to hyperchloremia and non-hyperchloremia groups according to the occurrence of hyperchloremia (i.e., ≥110 mEq/L) immediately after surgery. Poor early graft recovery was defined as estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2 during the first 48 hours after surgery. After PS matching, no significant differences in perioperative recipient or donor graft parameters were observed between groups. Although the total amount of crystalloid fluid infused during surgery did not differ between groups, the proportions of main crystalloid fluid type used (i.e., 0.9% normal saline vs. Plasma Solution-A) did. The eGFR increased gradually during postoperative day (POD) 2 in both groups. However, the proportion of patients with eGFR > 60 mL/min/1.73 m2 on POD 2 was higher in the non-hyperchloremia group than in the hyperchloremia group. In this PS-adjusted analysis, hyperchloremia was significantly associated with poor graft recovery on POD 2. In conclusion, exposure to hyperchloremia may have a negative impact on early graft recovery in LDKT.


Author(s):  
Aleksandra Tomaszek ◽  
Aleksandra Wróblewska ◽  
Elżbieta Zdankiewicz-Ścigała ◽  
Patryk Rzońca ◽  
Robert Gałązkowski ◽  
...  

The aim of this study was to determine the role of resilience and alexithymia in the post-traumatic growth as a response to extreme stress in patients after kidney transplantation and to determine whether there are differences in the level of posttraumatic growth in patients after living and cadaveric donor kidney transplantation. The relationships between these variables were also evaluated. The questionnaire survey of 91 kidney recipients took place in 2018 and 2019. The following tools were used: authorial post-transplant questionnaire for recipients and validated questionnaires, Post Traumatic Growth Inventory (PTGI-R), Resilience Coping Scale Questionnaire, and Toronto Alexithymia Scale Questionnaire (TAS20). The results obtained showed significant differences between the group of kidney recipients from living donors and recipients from cadaveric donors, in terms of overall post-traumatic growth, as well as changes in self-perception and a greater appreciation for life. Post-traumatic growth in both groups was related to the level of resilience and the level of alexithymia. Resilience is an accurate predictor of posttraumatic growth in general and for each of the groups of recipients separately.


2000 ◽  
Vol 32 (7) ◽  
pp. 1833-1834
Author(s):  
W.H Cho ◽  
H.T Kim ◽  
C.Y Sohn ◽  
S.H Joo ◽  
S.B Park ◽  
...  

2010 ◽  
Vol 42 (4) ◽  
pp. 1093-1094 ◽  
Author(s):  
F. Catena ◽  
L. Ansaloni ◽  
A. Amaduzzi ◽  
F. Gazzotti ◽  
M. Del Gaudio ◽  
...  

2020 ◽  
pp. 1-7
Author(s):  
Mireia Musquera Felip ◽  
Tarek Ajami Fardoun ◽  
Lluis Peri Cusi ◽  
Antonio Alcaraz Asensio

<b><i>Objective:</i></b> The aim of the study was to describe the surgical technique of totally robotic kidney transplantation with transvaginal insertion and to assess its safety and feasibility. <b><i>Methods:</i></b> It is a prospective analysis of the first 5 cases of robotic kidney transplantation with transvaginal insertion. Robotic-assisted kidney transplantation was performed after transvaginal insertion of a living donor kidney graft. Donor’s and recipient’s characteristics, intraoperative variables, postoperative complications, and surgical outcomes were assessed. <b><i>Results:</i></b> The median operative time was 220 min. Mean rewarming ischemia time of 53 min, with immediate diuresis. No intraoperative complications were observed. Mean hospitalization period was 9 days, with mean Cr of 1.5 mg/dL at discharge. <b><i>Conclusions:</i></b> Robotic kidney transplantation with transvaginal insertion is feasible and safe. A greater number of procedures are required to confirm the results of this new technique.


2020 ◽  
Vol 76 (5) ◽  
pp. 616-623 ◽  
Author(s):  
Allan B. Massie ◽  
Babak J. Orandi ◽  
Madeleine M. Waldram ◽  
Xun Luo ◽  
Anh Q. Nguyen ◽  
...  

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