Biomechanical tests for studying contractility and viscoelastic properties of single cardiac muscle cells

2020 ◽  
Author(s):  
Denis Volzhaninov ◽  
Anastasia Khokhlova
Keyword(s):  
Cardiac Muscle ◽  
Viscoelastic Properties ◽  
Muscle Cells ◽  
Cardiac Muscle Cells ◽  
Biomechanical Tests

Quantification of Diastolic Viscoelastic Properties of Isolated Cardiac Muscle Cells

2001 ◽  
Author(s):  
Catalin F. Baicu ◽  
Michael R. Zile
Keyword(s):  
Cardiac Muscle ◽  
Viscoelastic Properties ◽  
Three Dimensional ◽  
Pressure Overload ◽  
Muscle Cells ◽  
Elastic Stiffness ◽  
Experimental Conditions ◽  
Cardiac Muscle Cells ◽  
Diastolic Properties

Abstract Pathological processes which cause diastolic congestive heart failure (CHF), such as pressure overload hypertrophy (POH), produce abnormalities in the material properties of cardiac muscle cells (cardiomyocytes) and may selectively alter its elastic stiffness, viscosity, or both. Previous methods used to characterize these cardiomyocyte viscoelastic properties were constrained by specific biological and engineering limitations, which prevented testing in conditions that mimic normal physiology. The current study proposes an uniaxial variable-rate stretching method, in which isolated cardiomyocytes embedded in a three-dimensional gel matrix were subjected to stretch. Physiological Ca++ (2.5 mM) and rapid stretch rates up to 100 μm/sec provided experimental conditions parallel to in vivo physiology. The proposed method identified and individually quantified both cellular stiffness and viscosity, and showed that POH increased both elastic and viscous cardiomyocyte diastolic properties.

THE EFFECTS OF ACUPUNCTURE ON CARDIAC MUSCLE CELLS AND BLOOD PRESSURE IN SPONTANEOUS HYPERTENSIVE RATS

2004 ◽  
Vol 29 (1) ◽  
pp. 83-95 ◽  
Author(s):  
Hung-Chien Wu ◽  
Jaung-Geng Lin ◽  
Chun-Hsien Chu ◽  
Yung-Hsien Chang ◽  
Chung-Gwo Chang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiac Muscle ◽  
Muscle Cells ◽  
Hypertensive Rats ◽  
Cardiac Muscle Cells

Dendroaspis Natriuretic Peptide Induces the Apoptosis of Cardiac Muscle Cells

2005 ◽  
Vol 27 (1) ◽  
pp. 33-51 ◽  
Author(s):  
Ki-Chan Ha ◽  
Han-Jung Chae ◽  
Cheng-Shi Piao ◽  
Suhn-Hee Kim ◽  
Hyung-Ryong Kim ◽  
...  
Keyword(s):  
Cardiac Muscle ◽  
Natriuretic Peptide ◽  
Muscle Cells ◽  
Cardiac Muscle Cells

Microwave Radiation Effects on Cardiac Muscle Cells in Vitro

1981 ◽  
Vol 86 (2) ◽  
pp. 358 ◽  
Author(s):  
M. J. Galvin ◽  
C. A. Hall ◽  
D. I. McRee
Keyword(s):  
Cardiac Muscle ◽  
Microwave Radiation ◽  
Radiation Effects ◽  
Muscle Cells ◽  
Cardiac Muscle Cells

Contractile behaviors of cardiac muscle cells on mushroom-shaped micropillar arrays

2019 ◽  
Vol 174 ◽  
pp. 103-109 ◽  
Author(s):  
Nomin-Erdene Oyunbaatar ◽  
Arunkumar Shanmugasundaram ◽  
Dong-Weon Lee
Keyword(s):  
Cardiac Muscle ◽  
Muscle Cells ◽  
Cardiac Muscle Cells ◽  
Micropillar Arrays

scholarly journals Mdivi-1 attenuates sodium azide-induced apoptosis in H9c2 cardiac muscle cells

2017 ◽  
Vol 16 (5) ◽  
pp. 5972-5978 ◽  
Author(s):  
Xuehua Xu ◽  
Chengliang Luo ◽  
Zhixiang Zhang ◽  
Jun Hu ◽  
Xiangting Gao ◽  
...  
Keyword(s):  
Cardiac Muscle ◽  
Sodium Azide ◽  
Muscle Cells ◽  
Cardiac Muscle Cells ◽  
Induced Apoptosis
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