Synthesis of 2-Methylpyrrolo[1,2-a]pyrazin-1(2h)-one
The synthesis of 2-methylpyrrolo[1,2-a]pyrazin-1(2H)-one (2) present in the insect feeding deterrent peramine (1) through oxidation of the saturated lactam (3) is described. The preparation of the related 6- methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one (12) through a Lewis-acid- catalysed cyclization of the amide acetal (7) is also described.
1986 ◽
Vol 14
(3)
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pp. 287-289
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1995 ◽
Vol 4
(4)
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pp. 291-294
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1980 ◽
Vol 8
(1)
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pp. 73-75
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