Cognitive-Linguistic outcome in moderate to severe diffuse axonal injury and association with fatigue

Brain Injury ◽  
2022 ◽  
pp. 1-8
Author(s):  
Marjaana Raukola-Lindblom ◽  
Linda Ljungqvist ◽  
Timo Kurki ◽  
Olli Tenovuo ◽  
Marja Laasonen
Keyword(s):  
Axonal Injury ◽  
Diffuse Axonal Injury ◽  
Cognitive Linguistic

Traumatic or diffuse axonal injury? Author's response

2000 ◽  
Vol 26 (5) ◽  
pp. 491-491 ◽  
Author(s):  
J. F. Geddes ◽  
H. L. Whitwell ◽  
D. I. Graham
Keyword(s):  
Axonal Injury ◽  
Diffuse Axonal Injury

Radiological and cognitive characteristics of traumatic diffuse axonal injury

2006 ◽  
Vol 33 (S 1) ◽  
Author(s):  
R. Scheid ◽  
J.P. Schneider ◽  
D. Ott ◽  
K. Walther ◽  
T. Guthke ◽  
...  
Keyword(s):  
Axonal Injury ◽  
Diffuse Axonal Injury ◽  
Cognitive Characteristics

MRI of the diffuse axonal injury

1992 ◽  
Vol 28 (1) ◽  
pp. 61
Author(s):  
Yang Gu Joo ◽  
Young Hoon Woo ◽  
Soo Jhi Suh
Keyword(s):  
Axonal Injury ◽  
Diffuse Axonal Injury

Severe Diffuse Axonal Injury in Adults and Children

1994 ◽  
Vol 26 (3) ◽  
pp. 151-154 ◽  
Author(s):  
Tess Slazinski ◽  
Martin C. Johnson
Keyword(s):  
Axonal Injury ◽  
Diffuse Axonal Injury ◽  
Adults And Children

Comfort Measures for Severe Diffuse Axonal Injury: A Patient's Last Wish

2016 ◽  
Vol 7 (1) ◽  
pp. 64-68 ◽  
Author(s):  
William S. Baek
Keyword(s):  
Axonal Injury ◽  
Diffuse Axonal Injury

The Use of Antibodies Targeted Against the Neurofilament Subunits for the Detection of Diffuse Axonal Injury in Humans

1993 ◽  
Vol 52 (2) ◽  
pp. 143-152 ◽  
Author(s):  
M Sean Grady ◽  
Mark R. Mclaughlin ◽  
Carole W. Christman ◽  
Alex B. Valadka ◽  
Corinne L. Fligner ◽  
...  
Keyword(s):  
Axonal Injury ◽  
Diffuse Axonal Injury

Identifying Diffuse Axonal Injury by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight

2016 ◽  
Vol 37 (4) ◽  
pp. 279-283
Author(s):  
Guanheng Ren ◽  
Donghua Zou ◽  
Ping Huang ◽  
Zhengdong Li ◽  
Yu Shao ◽  
...  
Keyword(s):  
Axonal Injury ◽  
Diffuse Axonal Injury ◽  
Time Of Flight ◽  
Laser Desorption ◽  
Laser Desorption Ionization ◽  
Ionization Time ◽  
Desorption Ionization ◽  
Matrix Assisted Laser ◽  
Matrix Assisted Laser Desorption

Ubiquitin marks the reactive swellings of diffuse axonal injury

1993 ◽  
Vol 85 (5) ◽  
Author(s):  
JohnB. Schweitzer ◽  
MelburnR. Park ◽  
StephanieL. Einhaus ◽  
JamesT. Robertson
Keyword(s):  
Axonal Injury ◽  
Diffuse Axonal Injury

Diffuse Axonal Injury in Infants With Nonaccidental Craniocerebral Trauma

1999 ◽  
Vol 123 (2) ◽  
pp. 146-151 ◽  
Author(s):  
Aaron M. Gleckman ◽  
Michael D. Bell ◽  
Richard J. Evans ◽  
Thomas W. Smith
Keyword(s):  
Head Trauma ◽  
Axonal Injury ◽  
Diffuse Axonal Injury ◽  
Craniocerebral Trauma ◽  
Shaken Baby Syndrome ◽  
Normal Brain ◽  
Accurate Identification ◽  
Blunt Head Trauma ◽  
Hematoxylin Eosin ◽  
Axonal Swellings

Abstract Objective.—Accurate identification of diffuse axonal injury is important in the forensic investigation of infants who have died from traumatic brain injury. β-Amyloid precursor protein (β-APP) immunohistochemical staining is highly sensitive in identifying diffuse axonal injury. However, the effectiveness of this method in brain-injured infants has not been well established. The present study was undertaken to assess the utility of β-APP immunohistochemistry in detecting diffuse axonal injury in infants with either shaken baby syndrome or blunt head trauma. Materials and Methods.—Archival formalin-fixed, paraffin-embedded blocks from infants (<1 year old) with shaken baby syndrome (7 cases) and blunt head trauma (3) and blocks from 7 control cases that included nontraumatic cerebral edema (1), acute hypoxic-ischemic encephalopathy (1), and normal brain (5) were immunostained for β-APP. A semiquantitative assessment of the severity of axonal staining was made. Corresponding hematoxylin-eosin–stained sections were examined for the presence of axonal swellings. Results.—Immunostaining for β-APP identified diffuse axonal injury in 5 of 7 infants with shaken baby syndrome and 2 of 3 infants with blunt head trauma. Immunoreactive axons were easily identified and were present in the majority of the sections examined. By contrast, hematoxylin-eosin staining revealed axonal swellings in only 3 of 7 infants with shaken baby syndrome and 1 of 3 infants with blunt head trauma. Most of these sections had few if any visible axonal swellings, which were often overlooked on initial review of the slides. No β-APP immunoreactivity was observed in any of the 7 control cases. Conclusions.—Immunostaining for β-APP can easily and reliably identify diffuse axonal injury in infants younger than 1 year and is considerably more sensitive than routine hematoxylin-eosin staining. We recommend its use in the forensic evaluation of infants with fatal craniocerebral trauma.

Return to Work within Four Months of Grade 3 Diffuse Axonal Injury

2021 ◽  
Author(s):  
Michael Young ◽  
William Sanders ◽  
Rose Majuro ◽  
Yelena G. Bodien ◽  
Brian Edlow
Keyword(s):  
Return To Work ◽  
Axonal Injury ◽  
Diffuse Axonal Injury ◽  
Grade 3
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