Kinetic potentiometric determination of creatinine in serum with a picrate ion-selective membrane electrode.
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Abstract We describe a new kinetic method for potentiometric determination of creatinine in serum, based on the creatinine--picrate reaction in alkaline medium (Jaffé reaction). The reaction is monitored with a picrate-selective electrode, and the increase in electrode potential during 270 s is measured and related directly to the creatinine concentration. Small cation-exchange columns are used to separate creatinine from interfering substances. Analytical recovery of creatinine added to serum was 100.7%. Results for a series of samples compared well with results obtained with a spectrophotometric method (r = 0.994).
2019 ◽
Vol 12
(8)
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pp. 1839-1847
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2017 ◽
Vol 29
(2)
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pp. 375-380
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1971 ◽
Vol 56
(2)
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pp. 291-296
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2014 ◽
Vol 53
(39)
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pp. 14897-14903
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