Background: This study was conducted to evaluate the surgical
results of the arterial switch operation for Taussig-Bing variants, at a
single institution in a lower-middle income country. Methods:
Between June 2010 and December 2018, all consecutive patients diagnosed
with Taussig-Bing variants who underwent the arterial switch operation
and ventricular septal defect closure were included in the study.
Results: A total of 72 patients of Taussig-Bing variants who
underwent arterial switch operation and ventricular septal defect
closure. There were 10 early deaths (13.9%) and 2 late deaths (2.8%).
Intraoperative ventricular septal defect enlargement [hazard ratio
(HR) 7.23, 95% confidence interval (CI) 3.1294-16.7167; P
< 0.001], secondary aortic cross clamping (HR 28.38, 95% CI
4.8427-166.3484; P < 0.001), post-operative pneumonia
(HR 5.64, 95% CI 1.2724-24.9917; P = 0.023), and post-operative
sepsis (HR 5.28, 95% CI 1.3512-20.6553; p = 0.017) were risk factors
for overall mortality by competing risk analysis. Sixty patients
(83.3%) required septoparietal trabeculation division/resection during
the arterial switch operation in an attempt to avoid right ventricular
outflow tract obstruction. The reoperation rate for right ventricular
outflow tract obstruction at last follow up was 6% (3 patients). The
estimated freedom from reoperation for right ventricular outflow tract
obstruction at 1 year, 5 year and 9 year was 98.3%, 91.9% and 91.9 ,
respectively. Conclusions: The results of arterial switch
operation for Taussig-Bing variants were satisfactory in the operative
setting of a lower-middle income country, and performing extensive
septoparietal trabeculation division might reduce the reintervention
rate for right ventricular outflow tract obstruction in these patients.