Small vessel vasculitis

2020 ◽  
pp. 4573-4579
Author(s):  
Richard A. Watts
Keyword(s):  
Antineutrophil Cytoplasmic Antibody ◽  
Consensus Conference ◽  
Small Vessel ◽  
Small Vessel Vasculitis ◽  
Iga Vasculitis ◽  
Small Vessels ◽  
Chapel Hill ◽  
Familial Association ◽  
Chapel Hill Consensus Conference ◽  
Inflammatory Drugs

Small vessel vasculitis is vasculitis affecting predominately small intraparenchymal arteries, arterioles, capillaries, and venules. There are two main types: antineutrophil cytoplasmic antibody associated and immune complex mediated. The ANCA associated vasculitides are discussed in chapter 19.3 IgA vasculitis (IgAV) was formerly known as Henoch Schönlein purpura. The revised nomenclature reflects the importance of IgA vasculitis in pathogenesis. The Chapel Hill Consensus Conference defined IgA vasculitis as ‘vasculitis with IgA1-dominant immune deposits, affecting small vessels (predominantly capillaries, venules, or arterioles)’. IgA vasculitis often involves skin and gut, and frequently causes arthritis. Glomerulonephritis indistinguishable from IgA nephropathy may occur. Its aetiology is unknown, but it frequently occurs after an infection several days to weeks before. The most frequently isolated organism is beta-haemolytic streptococcus. Drugs such as a penicillin, ampicillin, erythromycin, and non-steroidal anti-inflammatory drugs have been reported as precipitating agents. There is an association with HLA-DRB1*01 in Caucasians and there appears to be a familial association.

scholarly journals Proposal for a more practical classification of antineutrophil cytoplasmic antibody-associated vasculitis

2020 ◽  
Author(s):  
Nestor Oliva-Damaso ◽  
Andrew S Bomback
Keyword(s):  
Granulomatosis With Polyangiitis ◽  
Clinical Information ◽  
Antineutrophil Cytoplasmic Antibody ◽  
Consensus Conference ◽  
Eosinophilic Granulomatosis With Polyangiitis ◽  
Chapel Hill ◽  
Chapel Hill Consensus Conference ◽  
Eosinophilic Granulomatosis ◽  
Relapse Rates

Abstract The nomenclature for antineutrophil cytoplasmic antibody (ANCA)-associated kidney disease has evolved from honorific eponyms to a descriptive-based classification scheme (Chapel Hill Consensus Conference 2012). Microscopic polyangiitis, granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis do not correlate with presentation, response rates and relapse rates as when comparing myeloperoxidase versus leukocyte proteinase 3. Here we discuss the limitations of the currently used classification and propose an alternative, simple classification according to (i) ANCA type and (ii) organ involvement, which provides important clinical information of prognosis and outcomes.

Primary vasculitides

2018 ◽  
pp. 447-482
Author(s):  
Gavin Clunie ◽  
Nick Wilkinson ◽  
Elena Nikiphorou ◽  
Deepak R. Jadon
Keyword(s):  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Granulomatosis With Polyangiitis ◽  
Clinical Manifestations ◽  
Antineutrophil Cytoplasmic Antibody ◽  
Consensus Conference ◽  
Eosinophilic Granulomatosis With Polyangiitis ◽  
Chapel Hill ◽  
Primary Angiitis ◽  
Chapel Hill Consensus Conference

This chapter describes large, medium, and small vessel primary vasculitides. The 2012 Chapel Hill Consensus Conference nomenclature of vasculitis is introduced, and acts as a framework for more detailed descriptions of polymyalgia rheumatic and giant cell arteritis, polyarteritis nodosa (systemic and cutaneous), granulomatosis with polyangiitis, microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis, Takayasu arteritis, childhood-onset vasculitis, Kawasaki disease, Henoch–Schönlein purpura, and leucocytoclastic vasculitis. Other antineutrophil cytoplasmic antibody-associated vasculitides and primary angiitis of central nervous system in children are also covered. The epidemiology, aetiopathogenesis, classification criteria, presenting features, clinical manifestations, and management of these diseases are presented. In particular, diagnostic criteria for and mimics of polymyalgia rheumatic and giant cell arteritis are discussed in detail to permit rheumatologists and non-rheumatologists to confidently manage them.

scholarly journals 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides

2012 ◽  
Vol 65 (1) ◽  
pp. 1-11 ◽  
Author(s):  
J. C. Jennette ◽  
R. J. Falk ◽  
P. A. Bacon ◽  
N. Basu ◽  
M. C. Cid ◽  
...  
Keyword(s):  
Consensus Conference ◽  
Chapel Hill ◽  
Chapel Hill Consensus Conference

scholarly journals CT Features of Vasculitides Based on the 2012 International Chapel Hill Consensus Conference Revised Classification

2017 ◽  
Vol 18 (5) ◽  
pp. 786 ◽  
Author(s):  
Jee Hye Hur ◽  
Eun Ju Chun ◽  
Hyon Joo Kwag ◽  
Jin Young Yoo ◽  
Hae Young Kim ◽  
...  
Keyword(s):  
Consensus Conference ◽  
Chapel Hill ◽  
Chapel Hill Consensus Conference ◽  
Ct Features

scholarly journals 313. FULMINANT IGA VASCULITIS AS A CATASTROPHIC ANCA-NEGATIVE SMALL VESSEL VASCULITIS

Rheumatology ◽  
2019 ◽  
Vol 58 (Supplement_2) ◽  
Author(s):  
Naoto Yokogawa ◽  
Nanase Honda ◽  
Kota Shimada ◽  
Shoji Sugii
Keyword(s):  
Small Vessel ◽  
Small Vessel Vasculitis ◽  
Iga Vasculitis

scholarly journals Development and initial evaluation of a measure of self-management for adults with antineutrophil cytoplasmic antibody-associated small-vessel vasculitis

2007 ◽  
Vol 57 (7) ◽  
pp. 1296-1302 ◽  
Author(s):  
Carolyn T. Thorpe ◽  
Robert F. Devellis ◽  
Megan A. Lewis ◽  
Susan J. Blalock ◽  
Susan L. Hogan ◽  
...  
Keyword(s):  
Antineutrophil Cytoplasmic Antibody ◽  
Initial Evaluation ◽  
Small Vessel ◽  
Self Management ◽  
Small Vessel Vasculitis
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