Ochronotic arthropathy in alkaptonuria

Rheumatology ◽  
2020 ◽  
Author(s):  
M Adam Ali ◽  
Richard Stratton
2021 ◽  
pp. 1-10
Author(s):  
Tuba Yuce Inel ◽  
Pelin Teke Kisa ◽  
Ali Balci ◽  
Sadettin Uslu ◽  
Zumrut Arslan ◽  
...  

1969 ◽  
Vol 2 (2) ◽  
pp. 96-97 ◽  
Author(s):  
B. R. Entwisle ◽  
K. D. Muirden ◽  
W. R. Adam ◽  
J. D. Parkin

2000 ◽  
Vol 15 (4) ◽  
pp. 539-543 ◽  
Author(s):  
Semih Aydoğdu ◽  
Emre Cullu ◽  
M.Hakan Özsoy ◽  
Hakkı Sur

Author(s):  
Josephina A. Vossen

Chapter 39 discusses alkaptonuria (ochronosis), a rare hereditary metabolic disease that leads to the deposition of homogentisic acid. Homogentisic acid accumulation causes damage to connective tissues; leads to formation of renal, urethral, and prostatic calculi; causes cardiovascular abnormalities; and causes arthropathy. Ochronotic arthropathy is the articular manifestation of alkaptonuria with the most common clinical sites of involvement being the spine, knees, and hips. Diagnosis of the disease is made by demonstration of homogentisic acid in the urine. Radiography is the standard method for detecting changes associated with alkaptonuria. CT can aid in the detection of intervertebral disc calcification.


2006 ◽  
Vol 26 (7) ◽  
pp. 1189-1191 ◽  
Author(s):  
Ichiro Shimizu ◽  
Tetsuo Hamada ◽  
Zain Khalpey ◽  
Keita Miyanishi ◽  
Toshihiko Hara

1965 ◽  
Vol 49 (1) ◽  
pp. 101-115 ◽  
Author(s):  
Mark N. Mueller ◽  
Leif B. Sorensen ◽  
Nels Strandjord ◽  
Attallah Kappas

2020 ◽  
Vol 30 (5) ◽  
pp. 923-929 ◽  
Author(s):  
Natesan Rajkumar ◽  
Dhanasekaran Soundarrajan ◽  
Palanisami Dhanasekararaja ◽  
Shanmuganathan Rajasekaran

1994 ◽  
Vol 18 (5) ◽  
pp. 467-471 ◽  
Author(s):  
Marco Melis ◽  
Paolo Onori ◽  
Giuseppe Aliberti ◽  
Emilio Vecci ◽  
Eugenio Gaudio

Sign in / Sign up

Export Citation Format

Share Document