scholarly journals Reliability and Validity of a 3-minute Psychomotor Vigilance Task (PVT) in Assessing Sensitivity to Sleep Loss and Alcohol: Fitness for Duty in Aviation and Transportation

SLEEP ◽  
2021 ◽  
Author(s):  
Sibylle Benderoth ◽  
Hans-Jürgen Hörmann ◽  
Caroline Schießl ◽  
Eva-Maria Elmenhorst

Abstract Study Objectives The psychomotor vigilance task (PVT) is a widely used objective method to measure sustained attention, but the standard 10-min version is often impractical in operational settings. We investigated the reliability and validity of a 3-min PVT administered on a portable handheld device assessing sensitivity to sleep loss and alcohol in relation to a 10-min PVT and to applied tasks. Methods Forty-seven healthy volunteers underwent a 12 consecutive days sleep lab protocol. A cross-over design was adopted including total sleep deprivation (TSD, 38 hours awake), sleep restriction (SR, 4 h sleep opportunity), acute alcohol consumption, and SR after alcohol intake (SR/Alc 4 h sleep opportunity). Participants performed a 10-min and 3-min PVT and operationally-relevant tasks related to demands in aviation and transportation. Results Sleep loss resulted in significant performance impairments compared to baseline measurements detected by both PVT versions – particularly for mean speed (both p < .001) - and the operationally-relevant tasks. Similar effects were observed due to alcohol intake (speed: both p < .001). The 3-min and 10-min PVT results were highly correlated (speed: between r = .72 and r = .89). Three of four aviation related tasks showed robust correlations with the 3-min PVT. Correlations with the parameters of the task related to transportation were lower, but mainly significant. Conclusion The 3-min PVT showed a high reliability and validity in assessing sleep loss and alcohol induced impairments in cognitive performance. Thus, our results underline its usefulness as potential fitness for duty self-monitoring tool in applied settings.

2018 ◽  
Vol 115 (31) ◽  
pp. 8009-8014 ◽  
Author(s):  
Eva-Maria Elmenhorst ◽  
David Elmenhorst ◽  
Sibylle Benderoth ◽  
Tina Kroll ◽  
Andreas Bauer ◽  
...  

Trait-like differences in cognitive performance after sleep loss put some individuals more at risk than others, the basis of such disparities remaining largely unknown. Similarly, interindividual differences in impairment in response to alcohol intake have been observed. We tested whether performance impairments due to either acute or chronic sleep loss can be predicted by an individual’s vulnerability to acute alcohol intake. Also, we used positron emission tomography (PET) to test whether acute alcohol infusion results in an up-regulation of cerebral A1 adenosine receptors (A1ARs), similar to the changes previously observed following sleep deprivation. Sustained attention in the psychomotor vigilance task (PVT) was tested in 49 healthy volunteers (26 ± 5 SD years; 15 females) (i) under baseline conditions: (ii) after ethanol intake, and after either (iii) total sleep deprivation (TSD; 35 hours awake; n = 35) or (iv) partial sleep deprivation (PSD; four nights with 5 hours scheduled sleep; n = 14). Ethanol- versus placebo-induced changes in cerebral A1AR availability were measured in 10 healthy male volunteers (31 ± 9 years) with [18F]8-cyclopentyl-3-(3-fluoropropyl)-1-propylxanthine (CPFPX) PET. Highly significant correlations between the performance impairments induced by ethanol and sleep deprivation were found for various PVT parameters, including mean speed (TSD, r = 0.62; PSD, r = 0.84). A1AR availability increased up to 26% in several brain regions with ethanol infusion. Our studies revealed individual trait characteristics for being either vulnerable or resilient to both alcohol and to sleep deprivation. Both interventions induce gradual increases in cerebral A1AR availability, pointing to a potential common molecular response mechanism.


2008 ◽  
Vol 40 (1) ◽  
pp. 347-352 ◽  
Author(s):  
Nicole Lamond ◽  
Sarah M. Jay ◽  
Jillian Dorrian ◽  
Sally A. Ferguson ◽  
Gregory D. Roach ◽  
...  

2017 ◽  
Vol 22 (2) ◽  
pp. 329-335 ◽  
Author(s):  
Takuro Kitamura ◽  
Soichiro Miyazaki ◽  
Hiroshi Kadotani ◽  
Takashi Kanemura ◽  
Harun Bin Sulaiman ◽  
...  

2012 ◽  
Vol 7 (4) ◽  
pp. 157-162
Author(s):  
Vanita C Ramrakhiyani ◽  
Abhijit G Deshpande ◽  
Prajakta A Deshpande ◽  
Prasad C Karnik

2018 ◽  
Vol 304 ◽  
pp. 39-45 ◽  
Author(s):  
Jaques Reifman ◽  
Kamal Kumar ◽  
Maxim Y. Khitrov ◽  
Jianbo Liu ◽  
Sridhar Ramakrishnan

2010 ◽  
Vol 25 ◽  
pp. 1130
Author(s):  
A. Wichniak ◽  
A. Wierzbicka ◽  
E. Waliniowska ◽  
I. Musinska ◽  
K. Czasak ◽  
...  

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