Acellular pertussis vaccine as a booster dose for seventeen- to nineteen-month-old children immunized with either whole cell or acellular pertussis vaccine at two, four and six months of age

1995 ◽  
Vol 14 (9) ◽  
pp. 792-796 ◽  
Author(s):  
SCOTT A. HALPERIN ◽  
ELAINE MILLS ◽  
LUIS BARRETO ◽  
CAROLYN PIM ◽  
BRIAN J. EASTWOOD
Keyword(s):  
Pertussis Vaccine ◽  
Booster Dose ◽  
Acellular Pertussis Vaccine ◽  
Whole Cell

Primary Immunization of Infants With an Acellular Pertussis Vaccine in a Double-Blind Randomized Clinical Trial

PEDIATRICS ◽  
1988 ◽  
Vol 82 (3) ◽  
pp. 293-299
Author(s):  
Margareta Blennow ◽  
Marta Granström ◽  
Eva Jäätmaa ◽  
Patrick Olin
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Pertussis Vaccine ◽  
Acellular Pertussis Vaccine ◽  
Cell Vaccine ◽  
Primary Immunization ◽  
Double Blind ◽  
Whole Cell ◽  
Whole Cell Vaccine ◽  
Acellular Vaccine

The rate of adverse reactions and the immunogenicity of a two-component acellular pertussis vaccine as compared with a plain whole-cell vaccine and a placebo were evaluated for primary immunization in 319 6-month-old infants in a double-blind randomized clinical trial. The acellular vaccine produced few and mild systemic and local reactions. Fever (≥38°C) occurred in 6% to 8% of acellular vaccinees as opposed to 25% to 37% of whole-cell vaccinees. Redness (≥1 cm) appeared in 2% to 13% of the acellular vaccine and 24% to 32% of the whole-cell vaccine recipients. Antibody response to pertussis toxin measured in a neutralization test was obtained in 97% to 100% of the infants receiving either two or three doses of the acellular vaccine as compared to 59% after three doses of whole-cell vaccine.

A decennial booster dose of reduced antigen content diphtheria, tetanus, acellular pertussis vaccine (Boostrix™) is immunogenic and well tolerated in adults

Vaccine ◽  
2010 ◽  
Vol 29 (1) ◽  
pp. 45-50 ◽  
Author(s):  
Robert Booy ◽  
Olivier Van Der Meeren ◽  
Su-Peing Ng ◽  
Froilan Celzo ◽  
Gunasekaran Ramakrishnan ◽  
...  
Keyword(s):  
Pertussis Vaccine ◽  
Booster Dose ◽  
Acellular Pertussis Vaccine

Comparison of whole-cell versus acellular pertussis vaccine effectiveness in school clusters of pertussis, France, 2013

2020 ◽  
Vol 50 (7) ◽  
pp. 617-619
Author(s):  
E. Belchior ◽  
S. Guillot ◽  
I. Poujol ◽  
A. Thabuis ◽  
L. Chouin ◽  
...  
Keyword(s):  
Pertussis Vaccine ◽  
Vaccine Effectiveness ◽  
Acellular Pertussis Vaccine ◽  
Whole Cell ◽  
Cell Versus

Dose–Response to a Two-Component Acellular Pertussis Vaccine In Infants and Comparison with Whole-cell Vaccine

Biologicals ◽  
1998 ◽  
Vol 26 (2) ◽  
pp. 145-153 ◽  
Author(s):  
Barry S Auerbach ◽  
Alan M Lake ◽  
Modena E Wilson ◽  
Field F Willingham ◽  
Jon Shematek ◽  
...  
Keyword(s):  
Pertussis Vaccine ◽  
Dose Response ◽  
Acellular Pertussis Vaccine ◽  
Cell Vaccine ◽  
Whole Cell ◽  
Two Component ◽  
Whole Cell Vaccine
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