Determination of Unbound Valproic Acid Concentration in Plasma by Equilibrium Dialysis and Gas—Liquid Chromatography

1982 ◽  
Vol 4 (4) ◽  
pp. 341-352 ◽  
Author(s):  
Roberto Riva ◽  
Fiorenzo Albani ◽  
Agostino Baruzzi ◽  
Ianna Galvani ◽  
Emilio Perucca
Keyword(s):  
Valproic Acid ◽  
Liquid Chromatography ◽  
Acid Concentration ◽  
Equilibrium Dialysis ◽  
Gas Liquid Chromatography ◽  
Valproic Acid Concentration

Determination of Valproic Acid by Flame-Ionization Gas-Liquid Chromatography

1979 ◽  
Vol 3 (3) ◽  
pp. 108-110 ◽  
Author(s):  
Gaylon A. Peyton ◽  
Steven C. Harris ◽  
Jack E. Wallace
Keyword(s):  
Valproic Acid ◽  
Liquid Chromatography ◽  
Gas Liquid Chromatography ◽  
Flame Ionization

Determination of free valproic acid concentration in 569 clinical samples by LC-MS/MS after HFCF-UF treatment

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Wu Xikun ◽  
Li Haoran ◽  
Dong Weichong ◽  
Yang Xiuling ◽  
Jin Yiran ◽  
...  
Keyword(s):  
Valproic Acid ◽  
Acid Concentration ◽  
Clinical Samples ◽  
Valproic Acid Concentration

scholarly journals Effect of Phenytoin on Protein Binding of Valproic Acid

1979 ◽  
Vol 6 (4) ◽  
pp. 453-454 ◽  
Author(s):  
J. Bruni ◽  
J.M. Gallo ◽  
B.J. Wilder
Keyword(s):  
Valproic Acid ◽  
Protein Binding ◽  
Acid Concentration ◽  
Equilibrium Dialysis ◽  
Free Fraction ◽  
In Vitro Experiments ◽  
Valproic Acid Concentration ◽  
Acid Protein ◽  
Dialysis Technique

SUMMARY:In vitro experiments using the equilibrium dialysis technique were performed to determine the binding of valproic acid to plasma components in the absence and presence of therapeutic concentrations of phenytoin. The free fraction of valproic acid was found to be dependent on the total valproic acid concentration. Phenytoin did not influence valproic acid protein binding.

scholarly journals Determination of Valproic Acid Concentration in Serum

1983 ◽  
Vol 9 (5) ◽  
pp. 375-378
Author(s):  
KUNIHIKO FUJIWARA ◽  
YOSHIAKI AKASAKA ◽  
KATSUO TAKAHASHI ◽  
MAKOTO IKEDA
Keyword(s):  
Valproic Acid ◽  
Acid Concentration ◽  
Valproic Acid Concentration
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