SUCCESSFUL TREATMENT OF EARLY POST-TRANSPLANT RECURRENT FOCAL SEGMENTAL GLOMERULOSCLEROSIS IN CHILDREN SIGNIFICANTLY IMPROVES LONG TERM GRAFT SURVIVAL.

2000 ◽  
Vol 69 (Supplement) ◽  
pp. S326
Author(s):  
Asher D. Schachter ◽  
William E. Harmon
2020 ◽  
Author(s):  
Thomas Mühlbacher ◽  
Kerstin Amann ◽  
Moritz Mahling ◽  
Silvio Nadalin ◽  
Nils Heyne ◽  
...  

Abstract Recurrence of primary focal segmental glomerulosclerosis (FSGS) occurs in up to 50% of patients after kidney transplantation and is associated with poor allograft outcome. Novel therapeutic concepts directly target podocyte function via B7-1 with inconsistent response. We present the case of a 19 yr. old patient with recurrent primary FSGS early after living donor kidney transplantation. Plasmapheresis and rituximab did not induce remission. Repetitive abatacept administration was able to achieve partial remission. Maintenance immunosuppression was subsequently switched to a belatacept-based CNI-free immunosuppression, resulting in sustained complete remission with excellent allograft function throughout a follow-up of more than 56 months.


2009 ◽  
Vol 25 (5) ◽  
pp. 957-959 ◽  
Author(s):  
Hiroshi Kaito ◽  
Koichi Kamei ◽  
Eriko Kikuchi ◽  
Masao Ogura ◽  
Kentaro Matsuoka ◽  
...  

2002 ◽  
Vol 17 (3) ◽  
pp. 165-168 ◽  
Author(s):  
M. Fujisawa ◽  
Kazumoto Iijima ◽  
Takeshi Ishimura ◽  
Akihiro Higuchi ◽  
Shuji Isotani ◽  
...  

2007 ◽  
Vol 22 (2) ◽  
pp. 215-221 ◽  
Author(s):  
Asiri S. Abeyagunawardena ◽  
Neil J. Sebire ◽  
R. Anthony Risdon ◽  
Michael J. Dillon ◽  
Lesley Rees ◽  
...  

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