Lower incidence and severity of cytomegalovirus-associated immune recovery uveitis in HIV-infected patients with delayed highly active antiretroviral therapy

AIDS ◽  
2005 ◽  
Vol 19 (7) ◽  
pp. 735-738 ◽  
Author(s):  
Gabriela Ortega-Larrocea ◽  
Enrique Espinosa ◽  
Gustavo Reyes-Terán
Keyword(s):  
Antiretroviral Therapy ◽  
Lower Incidence ◽  
Highly Active Antiretroviral Therapy ◽  
Immune Recovery ◽  
Immune Recovery Uveitis ◽  
Highly Active

scholarly journals Immune Recovery Uveitis Masked as an Endogenous Endophthalmitis in a Patient with Active CMV Retinitis

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Ligia Figueiredo ◽  
Renata Rothwell ◽  
Miguel Bilhoto ◽  
Rosário Varandas ◽  
Sofia Fonseca
Keyword(s):  
Highly Active Antiretroviral Therapy ◽  
Endogenous Endophthalmitis ◽  
Immune Recovery ◽  
Blurred Vision ◽  
Positive Polymerase Chain Reaction ◽  
Immune Recovery Uveitis ◽  
Cmv Retinitis ◽  
Highly Active ◽  
Polymerase Chain ◽  
The Right

Cytomegalovirus (CMV) retinitis may occur in profoundly immunocompromised patients and be the initial AIDS-defining infection. The incidence and prevalence of CMV retinitis has declined substantially in the era of highly active antiretroviral therapy (HAART); nevertheless, it remains a leading cause of ocular morbility. We report the case of a 40-year-old man with blurred vision and pain in the right eye, three weeks after the initiation of effective HAART treatment. Ocular examination revealed a panuveitis causing an anterior chamber reaction with hypopyon and a dense vitreous haze. An endogenous endophthalmitis was suspected and treatment was ensued, without improvement. A vitreous tap was performed, and a positive polymerase chain reaction for CMV was found. A diagnosis of immune recovery uveitis (IRU) was made, and the patient responded to treatment with valganciclovir and dexamethasone. IRU is an intraocular inflammation that develops in patients with HAART-induced immune recovery and inactive CMV retinitis, although cases of active CMV retinitis have been described. Presentation with panuveitis and hypopion is rare and may be misleading regarding diagnosis and management.

Cytokine profile in response to Cytomegalovirus associated with immune recovery syndrome after highly active antiretroviral therapy

2005 ◽  
Vol 40 (6) ◽  
pp. 711-720 ◽  
Author(s):  
Lilia S. Rios ◽  
Adriana L. Vallochi ◽  
Cristina Muccioli ◽  
M.A. Campos-Machado ◽  
Rubens Belfort ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Cytokine Profile ◽  
Immune Recovery ◽  
Highly Active

scholarly journals Evaluation of the impact of highly active antiretroviral therapy on immune recovery in antiretroviral naive patients

HIV Medicine ◽  
2004 ◽  
Vol 5 (1) ◽  
pp. 55-65 ◽  
Author(s):  
L Al-Harthi ◽  
J Voris ◽  
BK Patterson ◽  
S Becker ◽  
J Eron ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Immune Recovery ◽  
Highly Active ◽  
The Impact
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