Successful Treatment of Basilar Artery Thrombosis with Both Heparin and Tissue Plasminogen Activator in the Setting of Traumatic Vertebral Artery Dissection

2004 ◽  
Vol 57 (6) ◽  
pp. 1335-1337 ◽  
Author(s):  
Victor M. Erlich ◽  
David W. Newell
Author(s):  
Andrew P. Gasecki ◽  
Carmelo Graffagnino ◽  
Vladimir Hachinski ◽  
J.P Bahary

ABSTRACT:Background:Spontaneous dissection of the vertebral artery is uncommon.Method:Case study.Results:We report a 49-year-old woman who presented with the rapidly progressing basilar artery syndrome who was given an intravenous dose of tissue plasminogen activator seven hours after the onset of first symptoms. Thirty minutes after the injection, a dramatic recovery of the patient's consciousness and neurological signs was noted.Conclusion:To our knowledge, this is the first reported case of intravenous tissue plasminogen activator use in acute vertebral artery dissection.


1994 ◽  
Vol 41 (5) ◽  
pp. 358-361 ◽  
Author(s):  
Tomoaki Terada ◽  
Hideyuki Yokote ◽  
Mitsuharu Tsuura ◽  
Yasunobu Kinoshita ◽  
Yasuhiro Hayashi ◽  
...  

2014 ◽  
Vol 20 (3) ◽  
pp. 325-328 ◽  
Author(s):  
Arata Abe ◽  
Seiji Okubo ◽  
Shiro Onozawa ◽  
Masataka Nakajima ◽  
Kentaro Suzuki ◽  
...  

Few reports have described the successful treatment of stroke caused by acute vertebral artery (VA) origin occlusion by endovascular surgery. We describe the case of a 68-year-old man who experienced stroke due to left acute VA origin occlusion. Cerebral angiography showed that the left VA was occluded at its origin, the right VA had hypoplastic and origin stenosis, and the basilar artery was occluded by a thrombus. The VA origin occlusion was initially passed through with a 0.035-inch guide wire. An angioplasty was performed, and a coronary stent was appropriately placed. The VA origin was successfully recanalized. A balloon-assisted guiding catheter was navigated through the stent and a thrombectomy was performed using the Penumbra system. The patient's symptoms gradually improved postoperatively. Balloon-assisted catheter guidance through a vertebral artery stent permitted a successful thrombectomy using the Penumbra system and may be useful for treating stroke due to VA origin occlusion.


2005 ◽  
Vol 57 (suppl_4) ◽  
pp. ONS-E398-ONS-E398 ◽  
Author(s):  
Huan Wang ◽  
Kenneth Fraser ◽  
David Wang ◽  
Jorge Alvernia ◽  
Giuseppe Lanzino

Abstract OBJECTIVE AND IMPORTANCE: Basilar artery occlusion is a clinical event with an exceedingly high mortality rate. Improved survival is closely associated with successful recanalization of the occluded basilar artery. Bilateral vertebral artery occlusion (BVAO) is a unique disease entity that effectively denies any direct access to the basilar artery for endovascular rescue therapy. We report a case of successful intra-arterial basilar artery thrombolysis in a patient with BVAO. CLINICAL PRESENTATION: A 78-year-old man was transferred to our hospital after intravenous administration of tissue plasminogen activator and with deteriorating neurological status requiring intubation. His clinical presentation was highly suggestive of acute basilar artery thrombosis. The cerebral angiogram showed a BVAO and collateral flow reconstituting both distal extracranial vertebral arteries but with significant contrast stasis. There was no retrograde filling of the basilar artery through the only angiographically visible posterior communicating artery. TECHNIQUE: Selective catheterizations of the left occipital artery and the left ascending cervical branch of the thyrocervical trunk were performed to deliver a total of 12 mg of tissue plasminogen activator. At that point, the patient showed significant neurological improvement. The post-tissue plasminogen activator angiogram showed improved flow through the basilar artery. The patient was independent and well at his 1-year follow-up visit. CONCLUSION: Knowledge of potential collateral pathways is important when direct access to the main intracranial vessels is not available. Basilar artery thrombolysis through collateral vessels is clinically effective when a direct approach to the artery is not feasible.


2003 ◽  
Vol 143 (5) ◽  
pp. 649-652 ◽  
Author(s):  
Aviva Levitas ◽  
Nili Zucker ◽  
Eli Zalzstein ◽  
Shaul Sofer ◽  
Joseph Kapelushnik ◽  
...  

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