Endoscopic Lesser Saphenous Vein Harvesting for Coronary Artery Bypass Grafting: First Reported Case

Author(s):  
Christopher W. Nickum ◽  
Mercedes KC. Dullum ◽  
W. Douglas Boyd ◽  
Dana R. Gray

Endoscopic vessel harvesting has become a widely used modality for harvesting venous and arterial conduits for coronary artery bypass grafting. Specifically, it has been used to harvest the greater saphenous vein, internal thoracic artery, and the radial artery. A case of endoscopic lesser saphenous vein harvesting for coronary artery bypass grafting is reported.

2020 ◽  
Vol 8 (4) ◽  
pp. 183-189
Author(s):  
Sandra Kałużna ◽  
Mariusz J. Nawrocki ◽  
Rut Bryl ◽  
Katarzyna Stefańska ◽  
Marek Jemielity ◽  
...  

AbstractCoronary artery disease (CAD) is one of the leading causes of mortality in the world. The most advanced forms of CAD are usually treated by means of coronary artery bypass grafting (CABG). The selection of the appropriate vessels as aortocoronary conduits is of paramount importance. The internal thoracic artery (ITA) or the great saphenous vein (SV) are often harvested. Furthermore, epigenetic processes have been recently associated with atherosclerosis, hypertension, and heart failure, and post-translational histone processes may play a key role in understanding the genetic predisposition of vessels to vascular diseases.In the experiment performed, the transcript levels of JHDM1D, PHF8, and HDAC 1-3 in SV and ITA used for CABG procedures with RT-qPCR were examined. Total RNA was isolated by the method of Chomczyński and Sachi. RNA samples were reverse transcribed into cDNA using a commercial kit. The determination of the level of the transcripts of the mentioned genes was performed using the Light Cycler® 96 Real-Time PCR kit. Our analyzes confirmed that the studied genes related to post-translational modifications of histones are expressed in SV and ITA. In the saphenous vein, the expression of each of the individual genes was higher. The most considerable difference in transcript levels was recorded for HDAC1 and the smallest difference in expression for HDAC2.Our research suggests that more processes related to histone demethylation and acetylation occur in the saphenous vein, which may affect the selection of a vessel for CABG, but this research requires more research and additional analysis.Running title: Histone regulating gene expression in common coronary artery bypass graft vessels


Author(s):  
Robert F. Tranbaugh ◽  
Mario Gaudino ◽  
Brian F. Buxton ◽  
James Tatoulis

The radial artery is an easily harvested, versatile, and high-quality conduit with proven safety and efficacy during coronary artery bypass grafting. When properly harvested and deployed, the long-term patency is excellent and similar to the left internal thoracic artery. Either open or endoscopic harvesting may be used and target vessel stenosis should be at least 70%. Radial artery grafting is superior to saphenous vein grafting and appears to be equivalent to using the right internal thoracic artery. Adoption of radial artery grafting may be the most direct path to routine multiple arterial bypass grafting in the majority of patients undergoing coronary artery bypass grafting.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Nguyen Lam Vuong ◽  
Muhammed Khaled Elfaituri ◽  
Mohammed Eldoadoa ◽  
Sedighe Karimzadeh ◽  
Mohamed Ashraf Mokhtar ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document