scholarly journals (2S,4S)-4-Azido-1-benzyl-2-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]pyrrolidine

2006 ◽  
Vol 62 (7) ◽  
pp. o2983-o2985 ◽  
Author(s):  
Amy K. S. Chesterton ◽  
Sarah F. Jenkinson ◽  
Nigel A. Jones ◽  
George W. J. Fleet ◽  
David J. Watkin
Keyword(s):  
Absolute Configuration ◽  
Title Compound ◽  
Crystal Packing ◽  
Crystallographic Analysis ◽  
Starting Material ◽  
X Ray ◽  
Compound C ◽  
Relative Stereochemistry ◽  
The Absolute

The relative stereochemistry of the title compound, C16H22N4O2, a key intermediate in the synthesis of 3-deoxy imino sugars, was firmly established by X-ray crystallographic analysis. The absolute configuration was inferred from the starting material, D-galactose. There are no unusual crystal packing features.

scholarly journals 5-Amino-5-deoxy-2-C-hydroxymethyl-2,3-O-isopropylidene-L-lyxono-1,5-lactam

2007 ◽  
Vol 63 (3) ◽  
pp. o1409-o1411
Author(s):  
Michela Simone ◽  
George W. J. Fleet ◽  
Richard Bream ◽  
David J. Watkin
Keyword(s):  
Absolute Configuration ◽  
Catalytic Hydrogenation ◽  
Title Compound ◽  
Crystallographic Analysis ◽  
Starting Material ◽  
Relative Configuration ◽  
X Ray ◽  
Compound C ◽  
The Absolute

The relative configuration of the title compound, C9H14NO5, formed by catalytic hydrogenation of an azidolactone, has been established by X-ray crystallographic analysis. The absolute configuration was determined by the use of 2,3-O-isopropylidene-L-lyxono-1,4-lactone as the carbohydrate starting material.

scholarly journals N-Benzyl-3,5-dideoxy-3,5-imino-1,2-O-isopropylidene-β-L-lyxofuranose

2012 ◽  
Vol 68 (8) ◽  
pp. o2410-o2410
Author(s):  
David S. Edgeley ◽  
Sarah F. Jenkinson ◽  
Gabriel Lenagh-Snow ◽  
Catherine Rutherford ◽  
George W. J. Fleet ◽  
...  
Keyword(s):  
Absolute Configuration ◽  
Title Compound ◽  
Ring System ◽  
Starting Material ◽  
X Ray ◽  
X Ray Crystallography ◽  
Compound C ◽  
Relative Stereochemistry ◽  
The Absolute

X-ray crystallography confirmed the formation, structure and relative stereochemistry of the title compound, C15H19NO3, which contains a sterically congested four-membered azetidine ring system. The absolute configuration was determined by the use of L-arabinose as the starting material.

scholarly journals 2-N-Benzyl-2,6-dideoxy-2,6-imino-3,4-O-isopropylidene-D-allononitrile

2013 ◽  
Vol 69 (12) ◽  
pp. o1772-o1772 ◽  
Author(s):  
Benjamin J. Ayers ◽  
Sarah F. Jenkinson ◽  
George W. J. Fleet ◽  
Amber L. Thompson
Keyword(s):  
Absolute Configuration ◽  
Title Compound ◽  
Starting Material ◽  
Piperidine Ring ◽  
Boat Conformation ◽  
X Ray ◽  
X Ray Crystallography ◽  
Compound C ◽  
Relative Stereochemistry ◽  
Twisted Boat

X-ray crystallography firmly established the relative stereochemistry of the title compound, C16H20N2O3. The acetonide ring adopts an envelope conformation with one of the O atoms as the flap and the piperidine ring adopts a slightly twisted boat conformation. The absolute configuration was determined by use of D-ribose as the starting material. The compound exists as O—H...O hydrogen-bonded chains of molecules running parallel to thebaxis.

scholarly journals N-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-N-(3-azidopropyl)-O-methylhydroxylamine

2016 ◽  
Vol 72 (3) ◽  
pp. 340-342 ◽  
Author(s):  
Stefan Munneke ◽  
Bridget L. Stocker ◽  
Mattie S. M. Timmer ◽  
Graeme J. Gainsford
Keyword(s):  
Hydrogen Bonds ◽  
Absolute Configuration ◽  
Title Compound ◽  
Crystal Plate ◽  
Starting Material ◽  
Screw Axis ◽  
Compound C ◽  
The Absolute ◽  
Thin Crystal ◽  
Adequate Data

The structure of the title compound, C12H23N5O6, solved using adequate data from a thin crystal plate, confirmed that this useful glycoconjugate was obtained in the ring-closed β-pyranose configuration with4C1conformation. The molecules are bound by O—H...O(OH) hydrogen bonds, notably in a zigzagC(2) chain along the shortb(screw) axis, supplemented with anR22(12)O—H...O(carbonyl) link along theaaxis and otherC(2) links. The absolute configuration was not unambiguously determined but was known from the synthetic chemistry, which used natural 2-acetamido-2-deoxy-D-glucose as the starting material.

scholarly journals 2,4-Dimethyl-3,4-O-isopropylidene-L-arabinono-1,5-lactone

2007 ◽  
Vol 63 (3) ◽  
pp. o1128-o1130 ◽  
Author(s):  
Kathrine V. Booth ◽  
David J. Watkin ◽  
Sarah F. Jenkinson ◽  
George W. J. Fleet
Keyword(s):  
Absolute Configuration ◽  
Crystallographic Analysis ◽  
Starting Material ◽  
Relative Configuration ◽  
X Ray ◽  
Boat Form ◽  
The Absolute

The relative configuration at C-2 of 2,4-dimethyl-3,4-O-isopropylidene-L-arabinono lactone, C10H16O5, which exists in the boat form, was unequivocally established by X-ray crystallographic analysis. The absolute configuration was determined by the use of 2-C-methyl-D-ribonolactone as a starting material.

scholarly journals 2-Deoxy-2-fluoro-2-C-methyl-D-ribono-1,4-lactone (fluoromethylrib)

2006 ◽  
Vol 62 (4) ◽  
pp. o1208-o1210
Author(s):  
Samuel Parker ◽  
David Watkin ◽  
Benjamin Mayes ◽  
Richard Storer ◽  
Sarah Jenkinson ◽  
...  
Keyword(s):  
Title Compound ◽  
Crystallographic Analysis ◽  
Ring Size ◽  
X Ray ◽  
Compound C ◽  
Relative Stereochemistry

The relative stereochemistry of the fluoro substituent (as ribo) and the ring size of the lactone (as five) in the title compound, C6H9FO4, have been established by X-ray crystallographic analysis.

scholarly journals 5-O-tert-Butyldiphenylsilyl-2-C-hydroxymethyl-2,3-O-isopropylidene-2′-O-trifluoromethanesulfonyl-D-ribono-1,4-lactone

2007 ◽  
Vol 63 (3) ◽  
pp. o1088-o1090 ◽  
Author(s):  
Michela Simone ◽  
George W. J. Fleet ◽  
David J. Watkin
Keyword(s):  
Crystal Structure ◽  
Absolute Configuration ◽  
Title Compound ◽  
Starting Material ◽  
Compound C ◽  
The Absolute

The title compound, C26H31F3O8SSi, provides a unique example of the crystal structure of an organic trifluoromethanesulfonate attached to a primary C atom. The absolute configuration is determined by the use of D-ribose as the starting material.

4-(Bromomethyl)benzophenone

2007 ◽  
Vol 63 (3) ◽  
pp. o1188-o1189 ◽  
Author(s):  
Wei-Jian Xu ◽  
Yang-Ling Zang ◽  
Guo-Liang Wu ◽  
Sheng-Pei Su ◽  
De-Yue Qiu
Keyword(s):  
Crystal Structure ◽  
Carbon Tetrachloride ◽  
Dihedral Angle ◽  
Structure Analysis ◽  
Title Compound ◽  
Crystal Packing ◽  
Crystal Structure Analysis ◽  
X Ray ◽  
Compound C ◽  
Phenyl Rings

The title compound, C14H11BrO, was synthesized by the reaction of 4-methylbenzophenone and bromine in carbon tetrachloride. X-ray crystal structure analysis reveals that the benzene and phenyl rings form a dihedral angle of 59.53 (6)°, and the crystal packing is stabilized by intermolecular C—H...π interactions.

(3R,4R)-(–)-3-Hydroxymethyl-4-phenyl-2-o-toluoyl-1,2,3,4-tetrahydroisoquinoline

2006 ◽  
Vol 62 (5) ◽  
pp. o1774-o1776 ◽  
Author(s):  
Andrzej Gzella ◽  
Maria Chrzanowska ◽  
Agnieszka Dreas ◽  
Michał S. Kaczmarek ◽  
Zenon Woźniak
Keyword(s):  
Crystal Structure ◽  
Hydrogen Bonds ◽  
Absolute Configuration ◽  
Title Compound ◽  
Phenyl Ring ◽  
Heterocyclic Ring ◽  
Hydroxymethyl Group ◽  
Envelope Conformation ◽  
Compound C ◽  
The Absolute

The absolute configuration of the title compound, C24H23NO2, has been confirmed as 3R,4R. The hydroxymethyl group and phenyl ring at the asymmetric C atoms exhibit α and β orientations, respectively, and the non-planar heterocyclic ring of the tetrahydroisoquinoline system adopts an envelope conformation. The crystal structure is stabilized through hydrogen bonds.

(4S,1′R)-Diethyl 6-methyl-2-[(1′-phenylethylimino)methyl]-4-(2-thienyl)-1,4-dihydropyridine-3,5-dicarboxylate

2006 ◽  
Vol 62 (7) ◽  
pp. o2759-o2761
Author(s):  
Viktor Vrábel ◽  
Pavol Skubák ◽  
Štefan Marchalín ◽  
Vratislav Langer ◽  
Barbora Baumlová
Keyword(s):  
Hydrogen Bonds ◽  
Absolute Configuration ◽  
Title Compound ◽  
Thiophene Ring ◽  
Boat Conformation ◽  
Compound C ◽  
The Absolute

The absolute configuration of the title compound, C25H28N2O4S, has been determined. The molecules are interconnected by weak C—H...O hydrogen bonds. The 1,4-dihydropyridine (1,4-DHP) ring adopts the usual shallow boat conformation. The thiophene ring is nearly planar.

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