Large-scale Data Integration for Facilities Analytics: Challenges and Opportunities

2020 ◽  
Author(s):  
Balaje T. Thumati ◽  
Halasya Siva Subramania ◽  
Rajeev Shastri ◽  
Karthik Kalyana Kumar ◽  
Nicole Hessner ◽  
...  
Keyword(s):  
Data Integration ◽  
Large Scale ◽  
Large Scale Data ◽  
Challenges And Opportunities ◽  
Scale Data

scholarly journals Reconstructing SARS-CoV-2 response signaling and regulatory networks

2020 ◽  
Author(s):  
Jun Ding ◽  
Jose Lugo-Martinez ◽  
Ye Yuan ◽  
Darrell N. Kotton ◽  
Ziv Bar-Joseph
Keyword(s):  
Data Integration ◽  
Computational Methods ◽  
Regulatory Networks ◽  
Large Scale ◽  
Human Cells ◽  
Host Cells ◽  
Interaction Data ◽  
Large Scale Data ◽  
Different Types ◽  
Scale Data

AbstractSeveral molecular datasets have been recently compiled to characterize the activity of SARS-CoV-2 within human cells. Here we extend computational methods to integrate several different types of sequence, functional and interaction data to reconstruct networks and pathways activated by the virus in host cells. We identify the key proteins in these networks and further intersect them with genes differentially expressed at conditions that are known to impact viral activity. Several of the top ranked genes do not directly interact with virus proteins though some were shown to impact other coronaviruses highlighting the importance of large-scale data integration for understanding virus and host activity.Software and interactive visualization: https://github.com/phoenixding/sdremsc

scholarly journals Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme

10.1186/gm186 ◽  
2010 ◽  
Vol 2 (9) ◽  
pp. 65 ◽  
Author(s):  
Kristian Ovaska ◽  
Marko Laakso ◽  
Saija Haapa-Paananen ◽  
Riku Louhimo ◽  
Ping Chen ◽  
...  
Keyword(s):  
Glioblastoma Multiforme ◽  
Data Integration ◽  
Large Scale ◽  
Integration Framework ◽  
Comprehensive View ◽  
Large Scale Data ◽  
Scale Data

scholarly journals Robust classification of protein variation using structural modelling and large-scale data integration

2016 ◽  
Vol 44 (6) ◽  
pp. 2501-2513 ◽  
Author(s):  
Evan H. Baugh ◽  
Riley Simmons-Edler ◽  
Christian L. Müller ◽  
Rebecca F. Alford ◽  
Natalia Volfovsky ◽  
...  
Keyword(s):  
Data Integration ◽  
Large Scale ◽  
Structural Modelling ◽  
Robust Classification ◽  
Protein Variation ◽  
Large Scale Data ◽  
Scale Data

Large-scale Data Integration Using Graph Probabilistic Dependencies (GPDs)

2020 ◽  
Author(s):  
Muhammad Sadiq Hassan Zada ◽  
Bo Yuan ◽  
Ashiq Anjum ◽  
Muhammad Ajmal Azad ◽  
Wajahat Ali Khan ◽  
...  
Keyword(s):  
Data Integration ◽  
Large Scale ◽  
Large Scale Data ◽  
Scale Data
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