Automated unsupervised identification of cone photoreceptor cells in adaptive optics scanning laser ophthalmoscope images

Author(s):  
Yiwei Chen ◽  
Yi He ◽  
Jing Wang ◽  
Lina Xing ◽  
Guohua Shi
Author(s):  
Yiwei Chen ◽  
Yi He ◽  
Jing Wang ◽  
Wanyue Li ◽  
Lina Xing ◽  
...  

Cone photoreceptor cell identification is important for the early diagnosis of retinopathy. In this study, an object detection algorithm is used for cone cell identification in confocal adaptive optics scanning laser ophthalmoscope (AOSLO) images. An effectiveness evaluation of identification using the proposed method reveals precision, recall, and [Formula: see text]-score of 95.8%, 96.5%, and 96.1%, respectively, considering manual identification as the ground truth. Various object detection and identification results from images with different cone photoreceptor cell distributions further demonstrate the performance of the proposed method. Overall, the proposed method can accurately identify cone photoreceptor cells on confocal adaptive optics scanning laser ophthalmoscope images, being comparable to manual identification.


2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Yiwei Chen ◽  
Yi He ◽  
Jing Wang ◽  
Wanyue Li ◽  
Lina Xing ◽  
...  

The identification of cone photoreceptor cells is important for early diagnosing of eye diseases. We proposed automatic deep-learning cone photoreceptor cell identification on adaptive optics scanning laser ophthalmoscope images. The proposed algorithm is based on DeepLab and bias field correction. Considering manual identification as reference, our algorithm is highly effective, achieving precision, recall, and F 1 score of 96.7%, 94.6%, and 95.7%, respectively. To illustrate the performance of our algorithm, we present identification results for images with different cone photoreceptor cell distributions. The experimental results show that our algorithm can achieve accurate photoreceptor cell identification on images of human retinas, which is comparable to manual identification.


2013 ◽  
Vol 108 ◽  
pp. 1-9 ◽  
Author(s):  
Sung Pyo Park ◽  
Jae Keun Chung ◽  
Vivienne Greenstein ◽  
Stephen H. Tsang ◽  
Stanley Chang

2020 ◽  
Vol 11 (3) ◽  
pp. 1617 ◽  
Author(s):  
Sanam Mozaffari ◽  
Francesco LaRocca ◽  
Volker Jaedicke ◽  
Pavan Tiruveedhula ◽  
Austin Roorda

2019 ◽  
Vol 56 (2) ◽  
pp. 022202
Author(s):  
江慧绿 Jiang Huilü ◽  
李超宏 Li Chaohong ◽  
廖娜 Liao Na ◽  
厉以宇 Li Yiyu ◽  
陈浩 Chen Hao

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