Dry powders based on mucus-penetrating nanocomposite microparticles for pulmonary delivery of antibiotics

2015 ◽  
Author(s):  
Zimeng Wang ◽  
Samantha A. Meenach
Keyword(s):  
Pulmonary Delivery ◽  
Dry Powders ◽  
Nanocomposite Microparticles

scholarly journals Challenges Associated with the Pulmonary Delivery of Therapeutic Dry Powders for Preclinical Testing

2019 ◽  
Vol 36 (0) ◽  
pp. 129-144 ◽  
Author(s):  
Dominique N. Price ◽  
Nitesh K. Kunda ◽  
Pavan Muttil
Keyword(s):  
Pulmonary Delivery ◽  
Preclinical Testing ◽  
Dry Powders

Device factors affecting pulmonary delivery of dry powders

2013 ◽  
Vol 4 (8) ◽  
pp. 939-949 ◽  
Author(s):  
Chad C Smutney ◽  
Marshall Grant ◽  
P Spencer Kinsey
Keyword(s):  
Pulmonary Delivery ◽  
Dry Powders ◽  
Factors Affecting

Porous and highly dispersible voriconazole dry powders produced by spray freeze drying for pulmonary delivery with efficient lung deposition

2019 ◽  
Vol 560 ◽  
pp. 144-154 ◽  
Author(s):  
Qiuying Liao ◽  
Long Yip ◽  
Michael Y.T. Chow ◽  
Shing Fung Chow ◽  
Hak-Kim Chan ◽  
...  
Keyword(s):  
Freeze Drying ◽  
Pulmonary Delivery ◽  
Lung Deposition ◽  
Dry Powders ◽  
Spray Freeze Drying

scholarly journals Formulation of pH responsive peptides as inhalable dry powders for pulmonary delivery of nucleic acids

2014 ◽  
Vol 86 (1) ◽  
pp. 64-73 ◽  
Author(s):  
Wanling Liang ◽  
Philip C.L. Kwok ◽  
Michael Y.T. Chow ◽  
Patricia Tang ◽  
A. James Mason ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Pulmonary Delivery ◽  
Ph Responsive ◽  
Dry Powders

scholarly journals The Use of a Three-Fluid Atomising Nozzle in the Production of Spray-Dried Theophylline/Salbutamol Sulphate Powders Intended for Pulmonary Delivery

Pharmaceutics ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 1116
Author(s):  
Stefano Focaroli ◽  
Guannan Jiang ◽  
Peter O'Connell ◽  
John V. Fahy ◽  
Anne-Marie Healy
Keyword(s):  
Dry Powder Inhaler ◽  
Pulmonary Delivery ◽  
Spray Dryer ◽  
Equivalent Formulation ◽  
Dry Powders ◽  
Salbutamol Sulphate ◽  
Pharmaceutical Ingredients ◽  
Low Solubility ◽  
Two Fluid ◽  
Spray Dried

The aim of this study was to investigate the use of a three-fluid atomising nozzle in a lab-scale spray dryer for the production of dry powders intended for pulmonary delivery. Powders were composed of salbutamol sulphate and theophylline in different weight ratios. The three-fluid nozzle technology enabled powders containing a high theophylline content to be obtained, overcoming the problems associated with its relatively low solubility, by pumping two separate feed solutions (containing the two different active pharmaceutical ingredients (APIs)) into the spray dryer via two separate nozzle channels at different feed rates. The final spray-dried products were characterized in terms of morphology, solid-state properties and aerosolization performance, and were compared with an equivalent formulation prepared using a standard two-fluid atomising nozzle. Results confirmed that most of the powders made using the three-fluid atomising nozzle met the required standards for a dry powder inhaler formulation in terms of physical characteristics; however, aerosolization characteristics require improvement if the powders are to be considered suitable for pulmonary delivery.

scholarly journals Liposomal dry powders as aerosols for pulmonary delivery of proteins

2005 ◽  
Vol 6 (4) ◽  
pp. E641-E648 ◽  
Author(s):  
Dongmei Lu ◽  
Anthony J. Hickey
Keyword(s):  
Pulmonary Delivery ◽  
Dry Powders
Sign in / Sign up

Export Citation Format

Share Document