scholarly journals Retraction: “Evaluation of residual neuromuscular blockade using modified double burst stimulation” by Saitoh Y, Nakazawa K, Makita K, Tanaka H and Toyooka H

2019 ◽  
Vol 63 (4) ◽  
pp. 561-561

1997 ◽  
Vol 41 (6) ◽  
pp. 741-745 ◽  
Author(s):  
Y. SAITOH ◽  
K. NAKAZAWA ◽  
K. MAKITA ◽  
H. TANAKA ◽  
H. TOYOOKA


1990 ◽  
Vol 73 (3A) ◽  
pp. NA-NA ◽  
Author(s):  
E. P. Anderson ◽  
K. A. Jones ◽  
E. P. Stensrud ◽  
R. L. Lennon


Anaesthesia ◽  
1995 ◽  
Vol 50 (1) ◽  
pp. 23-25 ◽  
Author(s):  
A. K. JAIN ◽  
P. K. SHARMA ◽  
A. BHATTACHARYA


1990 ◽  
Vol 73 (3A) ◽  
pp. NA-NA
Author(s):  
K. A. Jones ◽  
R. L. Lennon ◽  
P. E. Stensrud ◽  
J. G. Weber ◽  
M. J. Joyner




2009 ◽  
Vol 110 (6) ◽  
pp. 1253-1260 ◽  
Author(s):  
Frank Herbstreit ◽  
Jürgen Peters ◽  
Matthias Eikermann

Background Residual neuromuscular blockade increases the risk to develop postoperative complications. The authors hypothesized that minimal neuromuscular blockade (train-of-four [TOF] ratio 0.5-1) increases upper airway collapsibility and impairs upper airway dilator muscle compensatory responses to negative pharyngeal pressure challenges. Methods Epiglottic and nasal mask pressures, genioglossus electromyogram, respiratory timing, and changes in lung volume were measured in awake healthy volunteers (n = 15) before, during (TOF = 0.5 and 0.8 [steady state]), and after recovery of TOF to unity from rocuronium-induced partial neuromuscular blockade. Passive upper airway closing pressure (negative pressure drops, random order, range +2 to -30 cm H2O) and pressure threshold for flow limitation were determined. Results Upper airway closing pressure increased (was less negative) significantly from baseline by 54 +/- 4.4% (means +/- SEM), 37 +/- 4.2%, and 16 +/- 4.1% at TOF ratios of 0.5, 0.8, and 1.0, respectively (P < 0.01 vs. baseline for any level). Phasic genioglossus activity almost quadrupled in response to negative (-20 cm H2O) pharyngeal pressure at baseline, and this increase was significantly impaired by 57 +/- 44% and 32 +/- 6% at TOF ratios of 0.5 and 0.8, respectively (P < 0.01 vs. baseline). End-expiratory lung volume, respiratory rate, and tidal volume did not change. Conclusion Minimal neuromuscular blockade markedly increases upper airway closing pressure, partly by impairing the genioglossus muscle compensatory response. Increased airway collapsibility despite unaffected values for resting ventilation may predispose patients to postoperative respiratory complications, particularly during airway challenges.





Sign in / Sign up

Export Citation Format

Share Document