Resolution of hypertension following water‐clear cell parathyroid adenoma excision

2021 ◽  
Author(s):  
Shipra Sankpal ◽  
Benjamin Scott ◽  
Henry R. E. Drysdale ◽  
Mark Kotowicz ◽  
Sonal Nagra ◽  
...  
Keyword(s):  
Parathyroid Adenoma ◽  
Clear Cell

Abstract #718: Obstacles to the Diagnosis of Water Clear Cell Parathyroid Adenoma: A Case Study

2017 ◽  
Vol 23 ◽  
pp. 141
Author(s):  
Timothy Reisner ◽  
Lindsey Rearigh ◽  
Carolyn Pease ◽  
Jan Franko ◽  
Daniela Frankova
Keyword(s):  
Parathyroid Adenoma ◽  
Clear Cell

scholarly journals Institutional characterisation of water clear cell parathyroid adenoma: a rare entity often unrecognised by TC-99m-sestamibi scintigraphy

Pathology ◽  
2021 ◽  
Author(s):  
C. Christofer Juhlin ◽  
Inga-Lena Nilsson ◽  
Henrik Falhammar ◽  
Jan Zedenius
Keyword(s):  
Parathyroid Adenoma ◽  
Clear Cell ◽  
Rare Entity ◽  
Sestamibi Scintigraphy

Chief cell and clear cell parathyroid adenoma do not influence clinical and biochemical expression of the sporadic primary hyperparathyroidism

Endocrine ◽  
2012 ◽  
Vol 43 (2) ◽  
pp. 440-443 ◽  
Author(s):  
Shweta Varshney ◽  
Sanjay Kumar Bhadada ◽  
Uma Nahar ◽  
Viral N. Shah ◽  
Anil Bhansali ◽  
...  
Keyword(s):  
Primary Hyperparathyroidism ◽  
Parathyroid Adenoma ◽  
Clear Cell ◽  
Chief Cell ◽  
Sporadic Primary Hyperparathyroidism

scholarly journals Water-clear cell parathyroid adenoma in a patient with acute pancreatitis

2014 ◽  
Vol 113 (11) ◽  
pp. 872-873 ◽  
Author(s):  
Yueh-Hung Chou ◽  
Jie-Yang Jhuang ◽  
Min-Shu Hsieh
Keyword(s):  
Acute Pancreatitis ◽  
Parathyroid Adenoma ◽  
Clear Cell

Water-clear-cell hyperplasia mimicking parathyroid adenoma

1985 ◽  
Vol 16 (10) ◽  
pp. 1075-1076 ◽  
Author(s):  
L. Clarke Stout
Keyword(s):  
Parathyroid Adenoma ◽  
Clear Cell ◽  
Cell Hyperplasia

scholarly journals Hypercalcemia in Pheochromocytoma: From MEN to VHL

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A997-A998
Author(s):  
Madhukar Mittal ◽  
Parul Gupta ◽  
Gautam R Chaudhary ◽  
Mahendra K Garg
Keyword(s):  
Primary Hyperparathyroidism ◽  
Parathyroid Adenoma ◽  
Cell Carcinoma ◽  
Adrenal Mass ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Renal Clear Cell Carcinoma ◽  
Adrenal Pheochromocytoma ◽  
Pancreatic Cystadenoma ◽  
Spinal Hemangioblastoma

Abstract Background: Co-occurrence of phaeochromocytoma and primary hyperparathyroidism is usually seen in patients of Multiple Endocrine neoplasia 2A(MEN2A) and is rare in Von Hippel Lindau disease (VHL). Parathyroid adenoma with pheochromocytoma in a genetically confirmed VHL has been reported only once till date (1). Clinical Case: A 30-year male was admitted for evaluation of hypertension and incidentally diagnosed adrenal mass on ultrasound. 9-years back, he was diagnosed as a case of VHL (right renal clear cell carcinoma, pancreatic cystadenoma, spinal hemangioblastoma and epididymal cysts). Right nephrectomy and pancreatic cyst excision had been done and past work-up for pheochromocytoma was normal. He also had been operated twice for recurrent renal calculi. Family history revealed surgery in mother for pancreatic mass. Current imaging revealed right adrenal mass (4.7*4.6 cm) with left renal cysts and calculi, pancreatic cysts and spinal- medullary hemangioblastoma and epididymal cysts. Fundus examination was normal. 24-hours urinary fractionated normetanephrines were elevated (2062 mcg/24 hours) and I131MIBG scan showed 4.7*4.6cm concentrating lesion in right renal fossa suggestive of right adrenal pheochromocytoma. However his biochemical evaluation revealed hypercalcemia (12.1 mg/dl), low phosphorus (3.2 mg/dl), low 25(OH) D (24.84 nmol/l), and raised PTH (121pg/ml). Ultrasound neck and Tc99m-Sestamibi localized left inferior parathyroid adenoma. DEXA scan showed severe osteoporosis. Genetic analysis confirmed VHL mutation in exon-1. Calcitonin and RET mutation were normal (ruled out MEN2A). Therapeutic approach was surgical excision of adrenal pheochromocytoma followed by parathyroidectomy. We report a case of pheochromocytoma with primary hyperparathyroidism (cause: left inferior parathyroid adenoma) in a patient of VHL (Renal clear cell carcinoma, pancreatic cystadenoma, epidydymal cysts and medullary and spinal hemangioblastoma). Hypercalcemia seen in patients of VHL is either due to bone metastasis/PTHrP/IL-6 secretion from RCC or due to PTHrP/PTH/calcitonin secretion from pheochromocytoma and rarely due to associated parathyroid adenoma. Literature search revealed four case reports of parathyroid adenoma with VHL. In only one of these, VHL had pheochromocytoma associated with parathyroid adenoma (1). Conclusion: Ours is the 2nd such case reported in literature of primary hyperparathyroidism in a genetically confirmed case of VHL with pheochromocytoma. This case highlights the overlap of tumorigenesis in two rare genetically divergent syndromes and importance of long-term follow-up for sequential development of new tumors. Reference: Arao T, Okada Yet al. A case of VHL disease with bilateral pheochromocytoma, renal cell carcinoma, pelvic tumor, spinal hemangioblastoma and primary hyperparathyroidism. Endocr J. 2002 Apr;49(2):181–8.

Water Clear Cell Parathyroid Adenoma: Case Report and Literature Review

2014 ◽  
Vol 03 (03) ◽  
Author(s):  
Patrick Tassone Seth Kaplan
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Parathyroid Adenoma ◽  
Clear Cell

Water-Clear Cell Parathyroid Adenoma Causing Primary Hyperparathyroidism in a Patient with Neurofibromatosis Type 1: Report of a Case

Surgery Today ◽  
2007 ◽  
Vol 37 (10) ◽  
pp. 884-887 ◽  
Author(s):  
Hitomi Kodama ◽  
Masatoshi Iihara ◽  
Takahiro Okamoto ◽  
Takao Obara
Keyword(s):  
Primary Hyperparathyroidism ◽  
Parathyroid Adenoma ◽  
Neurofibromatosis Type 1 ◽  
Clear Cell ◽  
Neurofibromatosis Type

Intrathyroidal water-clear cell parathyroid adenoma: A case report

2001 ◽  
Vol 32 (8) ◽  
pp. 889-892 ◽  
Author(s):  
Emine Dundar ◽  
Ronald T. Grenko ◽  
Aysen Akalin ◽  
Ertugrul Karahuseyinoglu ◽  
Kismet Bildirici
Keyword(s):  
Case Report ◽  
Parathyroid Adenoma ◽  
Clear Cell
Sign in / Sign up

Export Citation Format

Share Document