scholarly journals Effects of hemodynamic conditions and valve sizing on leaflet bending stress in self‐expanding transcatheter aortic valve: An in vitro study

2020 ◽  
Vol 44 (7) ◽  
Author(s):  
Viktória Stanová ◽  
Anne‐Sophie Zenses ◽  
Lionel Thollon ◽  
Lyes Kadem ◽  
Paul Barragan ◽  
...  
2017 ◽  
Vol 10 (3) ◽  
pp. S66
Author(s):  
Matheus Simonato ◽  
Ali Azadani ◽  
Michael Reardon ◽  
Gabriel Aldea ◽  
Georg Nickenig ◽  
...  

2016 ◽  
Vol 65 (03) ◽  
pp. 218-224
Author(s):  
Michael Scharfschwerdt ◽  
Roza Meyer-Saraei ◽  
Doreen Richardt ◽  
Efstratios Charitos ◽  
Hans-Hinrich Sievers ◽  
...  

2017 ◽  
Vol 153 (6) ◽  
pp. 1303-1315.e1 ◽  
Author(s):  
Ali N. Azadani ◽  
Michael Reardon ◽  
Matheus Simonato ◽  
Gabriel Aldea ◽  
Georg Nickenig ◽  
...  

Author(s):  
Neelakantan Saikrishnan ◽  
Nicole C. Milligan ◽  
Ajit P. Yoganathan

In about 1–2% of all live births, the human aortic valve only consists of two anomalous leaflets and is known as the bicuspid aortic valve (BAV). BAVs are the most common congenital cardiac anomaly, and are associated with significant valvular dysfunction, including calcific aortic stenosis (AS) and aortic regurgitation (AR), as well as aortic wall abnormalities including coarctation of the aorta, ascending aortic dilatation and aneurysms [1]. Many studies have proposed a common underlying genetic defect in progression of complications with BAVs [2]. However, other recent studies have also suggested that the altered hemodynamic environment associated with BAVs could also be responsible for accelerated disease progression in these patients [3, 4]. A recent in vitro study showed elevated levels of turbulence associated with BAVs, and indicated that fluid flow patterns in the aortic sinuses are also affected due to the altered valve morphology [5]. The present work seeks to compare the levels of turbulence in BAVs to pure trileaflet aortic stenosis models.


2004 ◽  
Vol 2004.5 (0) ◽  
pp. 185-186
Author(s):  
Shinnichi IIDA ◽  
Kenkichi OHBA ◽  
Tsutomu TAJIKAWA ◽  
Masataka YOSHIDA ◽  
Fuyo TSUKIYAMA

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