The first wide‐scale drug repurposing screen using the Prestwick Chemical Library (1200 bioactive molecules) against Neisseria gonorrhoeae identifies high in vitro activity of auranofin and many additional drugs

Apmis ◽  
2020 ◽  
Vol 128 (3) ◽  
pp. 242-250 ◽  
Author(s):  
Sunniva Foerster ◽  
Tomas N. Gustafsson ◽  
Anna Rita Brochado ◽  
Valentino Desilvestro ◽  
Athanasios Typas ◽  
...  
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Drug Repurposing ◽  
Bioactive Molecules ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Chemical Library ◽  
Wide Scale

scholarly journals In vitro activity of 14 antimicrobial agents against Neisseria gonorrhoeae from Spain.

1987 ◽  
Vol 63 (3) ◽  
pp. 215-216
Author(s):  
M C Lozano ◽  
J C Palomares ◽  
R Prados ◽  
E J Perea
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Antimicrobial Agents ◽  
Vitro Activity ◽  
In Vitro Activity

scholarly journals In vitro activity of a new fluoroquinolone, CP-99,219, against strains of Neisseria gonorrhoeae.

1995 ◽  
Vol 39 (4) ◽  
pp. 987-989 ◽  
Author(s):  
J S Knapp ◽  
S W Neal ◽  
M C Parekh ◽  
R J Rice
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Vitro Activity ◽  
In Vitro Activity

The susceptibilities of 216 strains of Neisseria gonorrhoeae to a new fluoroquinolone, CP-99,219 were determined. For strains for which the MICs of ciprofloxacin were < or = 0.06 microgram/ml, the MICs at which 90% of the isolates are inhibited (MIC90s) of CP-99,219, ciprofloxacin, and ofloxacin were 0.008, 0.015, and 0.03 microgram/ml, respectively. For strains for which the MICs of ciprofloxacin were 0.125 to 0.5 microgram/ml, the MIC90s of CP-99,219, ciprofloxacin, and ofloxacin were 0.06, 0.25, and 0.5 microgram/ml, respectively. For strains for which the MICs of ciprofloxacin and ofloxacin were 2.0 micrograms/ml, the MIC of CP-99,219 was 0.25 microgram/ml.

scholarly journals Comparative in vitro activity of Sch 29,482, a new oral penem, against Neisseria gonorrhoeae.

1983 ◽  
Vol 23 (3) ◽  
pp. 481-482 ◽  
Author(s):  
M Y Khan ◽  
R P Gruninger ◽  
S M Nelson ◽  
M L Simpson
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Vitro Activity ◽  
In Vitro Activity

In Vitro Activity of Sitafloxacin and Additional Newer Generation Fluoroquinolones Against Ciprofloxacin-Resistant Neisseria gonorrhoeae Isolates

2018 ◽  
Vol 24 (1) ◽  
pp. 30-34 ◽  
Author(s):  
Ryoichi Hamasuna ◽  
Makoto Ohnishi ◽  
Masahiro Matsumoto ◽  
Ryo Okumura ◽  
Magnus Unemo ◽  
...  
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Vitro Activity ◽  
In Vitro Activity
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