scholarly journals Influence of Particle Size of Deproteinized Bovine Bone Mineral on New Bone Formation and Implant Stability after Simultaneous Sinus Floor Elevation: A Histomorphometric Study in Minipigs

2013 ◽  
Vol 17 (2) ◽  
pp. 274-285 ◽  
Author(s):  
Simon S. Jensen ◽  
Merete Aaboe ◽  
Simone F. M. Janner ◽  
Nikola Saulacic ◽  
Michael M. Bornstein ◽  
...  
Keyword(s):  
Particle Size ◽  
Bovine Bone ◽  
New Bone Formation ◽  
Implant Stability ◽  
Sinus Floor Elevation ◽  
Histomorphometric Study ◽  
Sinus Floor ◽  
Bovine Bone Mineral ◽  
Deproteinized Bovine Bone Mineral ◽  
Deproteinized Bovine Bone

Maxillary Sinus Floor Elevation Surgery With BioOss Mixed With Enamel Matrix Derivative: A Human Randomized Controlled Clinical and Histologic Study

2020 ◽  
Vol 46 (5) ◽  
pp. 507-513
Author(s):  
Séverine Vincent-Bugnas ◽  
Yves Charbit ◽  
Mathieu Charbit ◽  
Michel Dard ◽  
Benjamin Pippenger
Keyword(s):  
Bone Mineral ◽  
Enamel Matrix Derivative ◽  
Bovine Bone ◽  
Enamel Matrix ◽  
Sinus Floor Augmentation ◽  
Sinus Floor ◽  
Bovine Bone Mineral ◽  
Deproteinized Bovine Bone Mineral ◽  
Matrix Derivative ◽  
Deproteinized Bovine Bone

Xenograft bone substitutes are commonly used to increase bone volume and height in the deficient posterior maxilla. The addition of enamel matrix derivate (Emdogain) could increase the efficiency of the bone healing process. The aim of this prospective randomized, controlled split-mouth design study was to compare the percentage of newly formed bone in sinus floor augmentation with deproteinized bovine bone mineral with or without the addition of enamel matrix derivative after 6 months of healing. Sixteen bilateral sinus floor augmentation procedures were performed. Deproteinized bovine bone mineral combined with enamel matrix derivative (test) and deproteinized bovine bone mineral alone (control) groups were randomly allocated within each patient. Six months after augmentation and concurrent to implant placement, bone biopsies were taken for histomorphometric analysis. Additionally, implant survival and peri-implant bone levels were radiographically assessed at baseline and 24 months after functional loading. Histomorphometric analysis revealed a significantly higher amount of newly formed bone in the test group compared with the control group (22.6% and 15.5%, respectively; P = .033). No significant differences in the amount of remaining graft or connective tissue was found. Enamel matrix derivative added to deproteinized bovine bone mineral particles significantly increased new bone formation in sinus lift procedures in edentulous or partially edentulous patients with deficient bilateral posterior alveolar ridges requiring augmentation for implant placement.

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