scholarly journals Active immunisation against GnRH as treatment for unilateral granulosa theca cell tumour in mares

2020 ◽  
Author(s):  
Daphne Behrendt ◽  
Dominik Burger ◽  
Steffen Gremmes ◽  
Katja Szunyog ◽  
Selena Röthemeier ◽  
...  
Keyword(s):  
Cell Tumour ◽  
Theca Cell ◽  
Active Immunisation

NEW VIEWS ON THE HORMONE-PRODUCING MESENCHYMOMAS OF THE OVARIES

1960 ◽  
Vol XXXV (IV) ◽  
pp. 513-517
Author(s):  
W. P. Plate
Keyword(s):  
Granulosa Cell ◽  
Sertoli Cell ◽  
Leydig Cell ◽  
Cell Tumour ◽  
Theca Cell ◽  
Granulosa Cell Tumour ◽  
Sertoli Cell Tumours ◽  
Leydig Cell Tumours

ABSTRACT The hormone-producing mesenchymomas of the ovaries can be divided into androblastomas and gynaecoblastomas. The former are derived from »male« elements, and consist of Sertoli-cell tumours and Leydig-cell tumours. The latter arise from »female« elements and consist of granulosacell tumours and theca-cell tumours. Sertoli-cell tumours and granulosacell tumours produce oestrogens, while Leydig-cell tumours and theca-cell tumours produce oestrogens or androgens. Histologically, androblastomas and gynaecoblastomas are often difficult to distinguish. Since no »female« elements occur in a testicle, a granulosa-cell tumour in a testicle is improbable. Gynandroblastomas, therefore, can only be found in an ovary.

Long-term outcome for two heifers with a granulosa-theca cell tumour

2013 ◽  
Vol 172 (22) ◽  
pp. 581.2-581 ◽  
Author(s):  
H. Dobson ◽  
M. J. Kerby ◽  
J. Chantrey ◽  
R. F. Smith
Keyword(s):  
Cell Tumour ◽  
Theca Cell ◽  
Term Outcome ◽  
Long Term Outcome

MALIGNANT THECA CELL TUMOUR OF THE OVARY

1961 ◽  
Vol 68 (6) ◽  
pp. 982-985 ◽  
Author(s):  
M. Sadek Foda ◽  
Abdel Fattah Youssef ◽  
M. A. Shafeek
Keyword(s):  
Cell Tumour ◽  
Theca Cell

Granulosa theca cell tumour in a pregnant mare: concentrations of inhibin and testosterone in serum before and after surgery

2012 ◽  
Vol 60 (2) ◽  
pp. 160-163 ◽  
Author(s):  
EK Gee ◽  
M Dicken ◽  
RM Archer ◽  
CL Herdan ◽  
FET Pauwels ◽  
...  
Keyword(s):  
Cell Tumour ◽  
Theca Cell ◽  
Before And After

STEROID BIOSYNTHESIS 'IN VITRO' BY GRANULOSA-THECA CELL TUMOUR TISSUE

1964 ◽  
Vol 30 (2) ◽  
pp. 247-NP ◽  
Author(s):  
K. GRIFFITHS ◽  
J. K. GRANT ◽  
T. SYMINGTON
Keyword(s):  
Major Metabolite ◽  
Cell Tumour ◽  
Theca Cell ◽  
Tumour Tissue ◽  
Menopausal Woman ◽  
Steroid Biosynthesis ◽  
Post Menopausal Woman ◽  
Post Menopausal

SUMMARY The metabolism of [4-14C]progesterone and [4-14C]androst-4-ene-3,17-dione (androstenedione) by a granulosa-theca cell tumour of the ovary, 310 g. in weight, removed from a 43-year-old post-menopausal woman has been studied in vitro. The experiments provided no evidence that the tumour could utilize progesterone as an oestrogen precursor. However, the tumour tissue converted androstenedione to oestrone and oestradiol-17β. The major metabolite of progesterone was 20α-hydroxypregn-4-en-3-one. These results are discussed in relation to current theories of the synthesis of steroids in the ovary.

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