Solid-phase synthesis and characterization of N-methyl-rich peptides

2008 ◽  
Vol 65 (2) ◽  
pp. 153-166 ◽  
Author(s):  
M. Teixidó ◽  
F. Albericio ◽  
E. Giralt
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Synthesis And Characterization ◽  
Phase Synthesis

Solid-phase synthesis and characterization of carcinoembryonic antigen (CEA) domains

2009 ◽  
Vol 52 (4) ◽  
pp. 249-260 ◽  
Author(s):  
B.E. Kaplan ◽  
L.J. Hefta ◽  
R.C. Blake II ◽  
K.M. Swiderek ◽  
J.E. Shively
Keyword(s):  
Carcinoembryonic Antigen ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Synthesis And Characterization ◽  
Phase Synthesis

Solid phase synthesis and characterization of new BIMEVOX series: Bi4V2−xMxO11 (M=Sbv, Nbv)

1994 ◽  
Vol 73 (3-4) ◽  
pp. 309-318 ◽  
Author(s):  
O JOUBERT ◽  
A JOUANNEAUX ◽  
M GANNE ◽  
R VANNIER ◽  
G MAIRESSE
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Synthesis And Characterization ◽  
Phase Synthesis

scholarly journals Electrophilic oligodeoxynucleotide synthesis using dM-Dmoc for amino protection

2019 ◽  
Vol 15 ◽  
pp. 1116-1128 ◽  
Author(s):  
Shahien Shahsavari ◽  
Dhananjani N A M Eriyagama ◽  
Bhaskar Halami ◽  
Vagarshak Begoyan ◽  
Marina Tanasova ◽  
...  
Keyword(s):  
Michael Addition ◽  
Steric Hindrance ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Side Product ◽  
Synthesis And Characterization ◽  
Protecting Group ◽  
Phase Synthesis ◽  
Improved Technology

Solid-phase synthesis of electrophilic oligodeoxynucleotides (ODNs) was achieved using dimethyl-Dmoc (dM-Dmoc) as amino protecting group. Due to the high steric hindrance of the 2-(propan-2-ylidene)-1,3-dithiane side product from deprotection, the use of excess nucleophilic scavengers such as aniline to prevent Michael addition of the side product to the deprotected ODN during ODN cleavage and deprotection was no longer needed. The improved technology was demonstrated by the synthesis and characterization of five ODNs including three modified ones. The modified ODNs contained the electrophilic groups ethyl ester, α-chloroamide, and thioester. Using the technology, the sensitive groups can be installed at any location within the ODN sequences without using any sequence- or functionality-specific conditions and procedures.

Solid phase synthesis and characterization of two canine gut gastrin-releasing peptides

2009 ◽  
Vol 32 (2) ◽  
pp. 141-152 ◽  
Author(s):  
R. C. DE L. MILTON ◽  
E. MAYER ◽  
J.H. WALSH ◽  
J.E. RIVIER ◽  
J. DYKERT ◽  
...  
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Synthesis And Characterization ◽  
Phase Synthesis
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