Analysis of the control of citrulline synthesis in isolated rat-liver mitochondria

1984 ◽  
Vol 142 (2) ◽  
pp. 247-254 ◽  
Author(s):  
Ronald J. A. WANDERS ◽  
Carlo W. T. ROERMUND ◽  
Alfred J. MEIJER
1989 ◽  
Vol 257 (1) ◽  
pp. 285-288 ◽  
Author(s):  
J D Johnston ◽  
M D Brand

1. In the presence of physiological concentrations of Na+ and Mg2+, the rate of citrulline synthesis by isolated rat liver mitochondria respiring on a range of substrates was stimulated by up to 60% when the extramitochondrial Ca2+ concentration was raised from 130 pM to 770 nM. 2. Our findings suggest that hormonal stimulation of the urea cycle may be mediated by Ca2+.


1983 ◽  
Vol 11 (1) ◽  
pp. 89-90 ◽  
Author(s):  
RONALD J. A. WANDERS ◽  
ALFRED J. MEIJER ◽  
CARLO M. VAN ROERMUND ◽  
ALBERT K. GROEN ◽  
COR LOF ◽  
...  

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