Some properties of site-specific mutants of human carbonic anhydrase II having active-site residues characterizing carbonic anhydrase III

1991 ◽  
Vol 201 (2) ◽  
pp. 417-420 ◽  
Author(s):  
Xilin REN ◽  
Bengt-Harald JONSSON ◽  
Sven LINDSKOG
Keyword(s):  
Carbonic Anhydrase ◽  
Active Site ◽  
Carbonic Anhydrase Ii ◽  
Active Site Residues ◽  
Site Specific ◽  
Carbonic Anhydrase Iii ◽  
Human Carbonic Anhydrase

scholarly journals Interactions of active-site residues and catalytic activity of human carbonic anhydrase III.

1994 ◽  
Vol 269 (37) ◽  
pp. 23002-23006
Author(s):  
C. Tu ◽  
X. Chen ◽  
X. Ren ◽  
P.V. LoGrasso ◽  
D.A. Jewell ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Carbonic Anhydrase ◽  
Active Site ◽  
Active Site Residues ◽  
Carbonic Anhydrase Iii ◽  
Human Carbonic Anhydrase

Role of histidine 64 in the catalytic mechanism of human carbonic anhydrase II studied with a site-specific mutant

Biochemistry ◽  
1989 ◽  
Vol 28 (19) ◽  
pp. 7913-7918 ◽  
Author(s):  
Chingkuang Tu ◽  
David N. Silverman ◽  
Cecilia Forsman ◽  
Bengt Harald Jonsson ◽  
Sven Lindskog
Keyword(s):  
Carbonic Anhydrase ◽  
Catalytic Mechanism ◽  
Carbonic Anhydrase Ii ◽  
Site Specific ◽  
Human Carbonic Anhydrase ◽  
A Site

Structural and kinetic analysis of proton shuttle residues in the active site of human carbonic anhydrase III

2007 ◽  
Vol 68 (1) ◽  
pp. 337-343 ◽  
Author(s):  
Ileana Elder ◽  
Zoë Fisher ◽  
Philip J. Laipis ◽  
Chingkuang Tu ◽  
Robert McKenna ◽  
...  
Keyword(s):  
Carbonic Anhydrase ◽  
Kinetic Analysis ◽  
Active Site ◽  
Carbonic Anhydrase Iii ◽  
Human Carbonic Anhydrase

Out of the active site binding pocket for carbonic anhydrase inhibitors

2015 ◽  
Vol 51 (2) ◽  
pp. 302-305 ◽  
Author(s):  
Katia D'Ambrosio ◽  
Simone Carradori ◽  
Simona M. Monti ◽  
Martina Buonanno ◽  
Daniela Secci ◽  
...  
Keyword(s):  
Carbonic Anhydrase ◽  
Active Site ◽  
Binding Pocket ◽  
Carbonic Anhydrase Ii ◽  
Carbonic Anhydrase Inhibitors ◽  
Human Carbonic Anhydrase ◽  
Site Binding

2-Benzylsulfinylbenzoic acid binds to human carbonic anhydrase II in a mode completely different from any other class of carbonic anhydrase inhibitors investigated so far.

scholarly journals Effect of Active-site Mutation at Asn67 on the Proton Transfer Mechanism of Human Carbonic Anhydrase II

Biochemistry ◽  
2009 ◽  
Vol 48 (33) ◽  
pp. 7996-8005 ◽  
Author(s):  
C. Mark Maupin ◽  
Jiayin Zheng ◽  
Chingkuang Tu ◽  
Robert McKenna ◽  
David N. Silverman ◽  
...  
Keyword(s):  
Carbonic Anhydrase ◽  
Proton Transfer ◽  
Active Site ◽  
Transfer Mechanism ◽  
Carbonic Anhydrase Ii ◽  
Site Mutation ◽  
Human Carbonic Anhydrase
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