CGS 30440: A Dual Inhibitor of Angiotensin-Converting Enzyme and Neutral Endopeptidase 24.11

Neutral Endopeptidase ◽

Converting Enzyme ◽

Dual Inhibitor ◽

Design and synthesis of phosphinic acids that triply inhibit endothelin converting enzyme, angiotensin converting enzyme and neutral endopeptidase 24.11

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/0960-894x(96)00297-1 ◽

1996 ◽

Vol 6 (14) ◽

pp. 1629-1634 ◽

Cited By ~ 27

Author(s):

Brian A. McKittrick ◽

Andrew W. Stamford ◽

Xiaoyu Weng ◽

Ke Ma ◽

Samuel Chackalamannil ◽

...

Keyword(s):

Neutral Endopeptidase ◽

Converting Enzyme ◽

Design And Synthesis ◽

Endopeptidase 24.11 ◽

Endothelin Converting Enzyme ◽

Phosphinic Acids

Effects of a dual inhibitor of angiotensin converting enzyme and neutral endopeptidase, MDL 100 240, on endocrine and renal functions in healthy volunteers

Journal of Hypertension ◽

10.1097/00004872-199917030-00017 ◽

1999 ◽

Vol 17 (3) ◽

pp. 427-437 ◽

Cited By ~ 23

Author(s):

Philippe Rousso ◽

Thierry Buclin ◽

Jürg Nussberger ◽

Laurent A. Décosterd ◽

Salome D. La Roche ◽

...

Keyword(s):

Healthy Volunteers ◽

Neutral Endopeptidase ◽

Converting Enzyme ◽

Dual Inhibitor ◽

Renal Functions

α-Mercaptoacyl dipeptides that inhibit angiotensin converting enzyme and neutral endopeptidase 24.11

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/0960-894x(95)00105-3 ◽

1995 ◽

Vol 5 (7) ◽

pp. 735-738 ◽

Cited By ~ 4

Author(s):

Shripad S. Bhagwat ◽

Cynthia A. Fink ◽

Candido Gude ◽

Kenneth Chan ◽

Ying Qiao ◽

...

Keyword(s):

Neutral Endopeptidase ◽

Converting Enzyme ◽

ChemInform Abstract: Diastereoselective Synthesis of Mixanpril, an Orally Active Dual Inhibitor of Neutral Endopeptidase and Angiotensin Converting Enzyme.

ChemInform ◽

10.1002/chin.199602247 ◽

2010 ◽

Vol 27 (2) ◽

pp. no-no

Author(s):

S. TURCAUD ◽

W. GONZALEZ ◽

J.-B. MICHEL ◽

B. P. ROQUES ◽

M.-C. FOURNIE-ZALUSKI

Keyword(s):

Neutral Endopeptidase ◽

Converting Enzyme ◽

Diastereoselective Synthesis ◽

Dual Inhibitor ◽

Orally Active

ChemInform Abstract: Design and Synthesis of Phosphinic Acids That Triply Inhibit Endothelin Converting Enzyme, Angiotensin Converting Enzyme and Neutral Endopeptidase 24.11.

ChemInform ◽

10.1002/chin.199646222 ◽

2010 ◽

Vol 27 (46) ◽

pp. no-no ◽

Cited By ~ 1

Author(s):

B. A. MCKITTRICK ◽

A. W. STAMFORD ◽

X. WENG ◽

K. MA ◽

S. CHACKALAMANNIL ◽

...

Keyword(s):

Neutral Endopeptidase ◽

Converting Enzyme ◽

Design And Synthesis ◽

Endopeptidase 24.11 ◽

Endothelin Converting Enzyme ◽

Phosphinic Acids

4-Substituted proline derivatives that inhibit angiotensin converting enzyme and neutral endopeptidase 24.11.

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(01)80694-6 ◽

1994 ◽

Vol 4 (22) ◽

pp. 2673-2676 ◽

Cited By ~ 10

Author(s):

Shripad S. Bhagwat ◽

Cynthia A. Fink ◽

Candido Gude ◽

Kenneth Chan ◽

Ying Qiao ◽

...

Keyword(s):

Neutral Endopeptidase ◽

Converting Enzyme ◽

Endopeptidase 24.11 ◽

Proline Derivatives

Mechanism of Vasopeptidase Inhibitor-Induced Plasma Extravasation: Comparison of Omapatrilat and the Novel Neutral Endopeptidase 24.11/Angiotensin-Converting Enzyme Inhibitor GW796406

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.105.084749 ◽

2005 ◽

Vol 315 (3) ◽

pp. 1306-1313 ◽

Cited By ~ 19

Author(s):

Anthony C. Sulpizio ◽

Mark A. Pullen ◽

Richard M. Edwards ◽

James B. Louttit ◽

Rob West ◽

...

Keyword(s):

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Neutral Endopeptidase ◽

Plasma Extravasation ◽

The Novel ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor ◽

Vasopeptidase Inhibitor ◽

Pulmonary Peptidases: General Principles of Peptide Metabolism and Molecular Biology of Angiotensin-Converting Enzyme, Neutral Endopeptidase 24.11, and Carboxypeptidase M

Neuropeptides in Respiratory Medicine ◽

10.4324/9780203745915-14 ◽

2017 ◽

pp. 301-312

Author(s):

Randal Skidgel

Keyword(s):

Molecular Biology ◽

Neutral Endopeptidase ◽

Converting Enzyme ◽

Endopeptidase 24.11 ◽

Peptide Metabolism ◽

Carboxypeptidase M

Pulmonary Peptidases: General Principles of Peptide Metabolism and Molecular Biology of Angiotensin-Converting Enzyme, Neutral Endopeptidase 24.11, and Carboxypeptidase M

Neuropeptides in Respiratory Medicine ◽

10.1201/9780203745915-13 ◽

2017 ◽

pp. 301-312

Author(s):

Randal A. Skidgel

Keyword(s):

Molecular Biology ◽

Neutral Endopeptidase ◽

Converting Enzyme ◽

Endopeptidase 24.11 ◽

Peptide Metabolism ◽

Carboxypeptidase M

ChemInform Abstract: Heterocyclic Lactam Derivatives as Dual Angiotensin Converting Enzyme and Neutral Endopeptidase 24.11 Inhibitors.

ChemInform ◽

10.1002/chin.199425166 ◽

2010 ◽

Vol 25 (25) ◽

pp. no-no

Author(s):

J. L. STANTON ◽

D. M. SPERBECK ◽

A. J. TRAPANI ◽

D. COTE ◽

Y. SAKANE ◽

...

Keyword(s):

Neutral Endopeptidase ◽

Converting Enzyme ◽