Primary pure pancreatic‐type acinar cell carcinoma of the stomach

2021 ◽  
Author(s):  
Shunsuke Uno ◽  
Yasuyuki Tanaka ◽  
Shinsuke Shibuya ◽  
Keijiro Okada ◽  
Shigehiko Fujii ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Acinar Cell ◽  
Acinar Cell Carcinoma ◽  
Carcinoma Of The Stomach

scholarly journals Pancreatic-Type Mixed Acinar Neuroendocrine Carcinoma of the Stomach: A Case Report And Review of Literature

2020 ◽  
Author(s):  
Yuka Ooe ◽  
Kishichiro WATANABE ◽  
Isaya HASHIMOTO ◽  
Satoshi TAKENAKA ◽  
Toshihiko OJIMA ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Neuroendocrine Carcinoma ◽  
Acinar Cell ◽  
Perioperative Complications ◽  
Gastric Gland ◽  
Acinar Cell Carcinoma ◽  
Pathological Examination ◽  
Gastric Body ◽  
Carcinoma Of The Stomach ◽  
Upper Gi Endoscopy

Abstract Background: A majority of gastrointestinal tumors are adenocarcinoma. Rarely, there is also a type of tumors such as acinar cell carcinoma, which are often called pancreatic-type acinar cell carcinoma. Among those, some are differentiated into neuroendocrine components. A few of them can be called MiNENs. Case presentation: The patient was an 80-year old male who was referred to our hospital for treatments of a pedunculated gastric tumor. It was 5 cm in diameter and detected in the upper gastric body with upper GI endoscopy conducted for investigation of anemia. In the biopsy, although a kind of hyperplasia of gastric gland cell was pointed out, no tumor cells were found. Retrospectively, the diagnosis was turned out to be a misdiagnosis. An operation was arranged because bleeding from the tumor was suspected as a cause of anemia and because a surgical resection was considered to be desirable for accurate diagnosis. Hence, laparoscopy and endoscopy cooperative surgery was performed. In pathological examination, several types of epithelial cells which proliferated in the area between mucosa and deep inside the submucosa were observed. These consisted of acinar-glandular/trabecular patterns and solid pattern. A diagnosis of pancreatic-type acinar cell carcinoma of the stomach with NET G2 and G3 was made based on characteristic cellular findings and the result of immunostaining tests. Each of them consisted of more than 30% of the lesion; a diagnosis of pancreatic-type mixed acinar neuroendocrine carcinoma (pancreatic-type MiNEN) of the stomach, or a type of gastric MiNEN was obtained. Anemia was resolved after operation, and the patient was discharged from the hospital without perioperative complications. Conclusions: Pancreatic-type ACC of the stomach which is differentiated into neuroendocrine tumor is very rare. Hence, we report this case along with several literature reviews.

Pure Pancreatic-Type Acinar Cell Carcinoma of the Stomach

2012 ◽  
Vol 20 (1) ◽  
pp. 71-73 ◽  
Author(s):  
John D Coyne
Keyword(s):  
Cell Carcinoma ◽  
Acinar Cell ◽  
Acinar Cell Carcinoma ◽  
Carcinoma Of The Stomach

scholarly journals A primary pure pancreatic-type acinar cell carcinoma of the stomach: a case report

2017 ◽  
Vol 12 (1) ◽  
Author(s):  
Kyoung Min Kim ◽  
Chan Young Kim ◽  
Seung-Mo Hong ◽  
Kyu Yun Jang
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Acinar Cell ◽  
Acinar Cell Carcinoma ◽  
Carcinoma Of The Stomach

Pancreatic-type acinar cell carcinoma of the stomach beneath a focus of pancreatic metaplasia of the gastric mucosa

2009 ◽  
Vol 40 (5) ◽  
pp. 746-749 ◽  
Author(s):  
Andrea Ambrosini-Spaltro ◽  
Oscar Potì ◽  
Michele De Palma ◽  
Marcello Filotico
Keyword(s):  
Gastric Mucosa ◽  
Cell Carcinoma ◽  
Acinar Cell ◽  
Acinar Cell Carcinoma ◽  
Carcinoma Of The Stomach

scholarly journals Title: pancreatic‐type mixed acinar neuroendocrine carcinoma of the stomach: a case report and review of the literature

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Yuka Ooe ◽  
Kishichiro Watanabe ◽  
Isaya Hashimoto ◽  
Satoshi Takenaka ◽  
Toshihiko Ojima ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Neuroendocrine Carcinoma ◽  
Acinar Cell ◽  
Perioperative Complications ◽  
Gastric Gland ◽  
Acinar Cell Carcinoma ◽  
Pathological Examination ◽  
Gastric Body ◽  
Carcinoma Of The Stomach ◽  
Upper Gi Endoscopy

Abstract Background The majority of gastrointestinal tumors are adenocarcinomas. Rarely, there are other types of tumors, such as acinar cell carcinoma, and these are often called pancreatic-type acinar cell carcinomas. Among these tumors, some are differentiated into neuroendocrine components. A few of them are MiNENs. Case presentation The patient was an 80-year-old male who was referred to our hospital for treatment of a pedunculated gastric tumor. It was 5 cm in diameter and detected in the upper gastric body with upper GI endoscopy conducted to investigate anemia. In the biopsy, although hyperplasia of gastric gland cells was noted, no tumor cells were found. Retrospectively, the diagnosis was misdiagnosed. An operation was arranged because bleeding from the tumor was suspected as a cause of anemia and because surgical resection was considered to be desirable for accurate diagnosis. Hence, laparoscopic and endoscopic cooperative surgery was performed. In the pathological examination, several types of epithelial cells that proliferated in the area between the mucosa and deep inside the submucosa were observed. These consisted of acinar-glandular/trabecular patterns and solid. A diagnosis of pancreatic-type acinar cell carcinoma of the stomach with NET G2 and G3 was made based on characteristic cellular findings and the results of immunostaining tests. Each of them consisted of more than 30% of the lesion; a diagnosis of pancreatic-type mixed acinar neuroendocrine carcinoma (pancreatic-type MiNEN) of the stomach or a type of gastric MiNEN was obtained. Anemia was resolved after the operation, and the patient was discharged from the hospital without perioperative complications. Conclusions Pancreatic-type ACC of the stomach that is differentiated into neuroendocrine tumors is very rare. Hence, we report this case along with a literature review.

scholarly journals Case report: Novel PIK3CA and AXIN1 mutations in acinar cell carcinoma of the stomach arising from pancreatic heterotopia

2021 ◽  
Vol 25 ◽  
pp. 200529
Author(s):  
Brian T Brinkerhoff ◽  
Mandy VanSandt ◽  
Skye C Mayo ◽  
Carol Beadling ◽  
Christopher L Corless
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Acinar Cell ◽  
Acinar Cell Carcinoma ◽  
Carcinoma Of The Stomach ◽  
Pancreatic Heterotopia

CT Findings of Acinar Cell Carcinoma of the Pancreas: Focused on Spiral CT Findings

2001 ◽  
Vol 45 (1) ◽  
pp. 29 ◽  
Author(s):  
Jong Young Oh ◽  
Kyung Jin Nam ◽  
Jong Cheol Choi ◽  
Suck Bin Suh ◽  
Ki Nam Lee ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Acinar Cell ◽  
Acinar Cell Carcinoma ◽  
Spiral Ct ◽  
Carcinoma Of The Pancreas ◽  
Ct Findings

Patients With Acinar Cell Carcinoma of the Pancreas After 2005

Pancreas ◽  
2020 ◽  
Vol 49 (6) ◽  
pp. 781-787
Author(s):  
Yuan Zong ◽  
Changsong Qi ◽  
Zhi Peng ◽  
Lin Shen ◽  
Jun Zhou
Keyword(s):  
Cell Carcinoma ◽  
Acinar Cell ◽  
Acinar Cell Carcinoma ◽  
Carcinoma Of The Pancreas
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