Metabolic Activation of the Indoloquinazoline Alkaloids Evodiamine and Rutaecarpine by Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4

2014 ◽  
Vol 42 (6) ◽  
pp. 1044-1054 ◽  
Author(s):  
Bo Wen ◽  
Vikram Roongta ◽  
Liling Liu ◽  
David J. Moore
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Metabolic Activation ◽  
Human Liver Microsomes ◽  
Cytochrome P450 3A4

Involvement of Cytochrome P450 3A4 Enzyme in theN-Demethylation of Methadone in Human Liver Microsomes

1996 ◽  
Vol 9 (2) ◽  
pp. 365-373 ◽  
Author(s):  
Christelle Iribarne ◽  
François Berthou ◽  
Susan Baird ◽  
Yvonne Dréano ◽  
Daniel Picart ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cytochrome P450 3A4

Procarcinogen activation by cytochrome P450 3A4 and 3A5 expressed in Escherichia coli and by human liver microsomes

1995 ◽  
Vol 16 (9) ◽  
pp. 2167-2170 ◽  
Author(s):  
Hiroshi Yamazaki ◽  
Yukiharu Inui ◽  
Steven A. Wrighton ◽  
F.Peter Guengerich ◽  
Tsutomu Shimada
Keyword(s):  
Escherichia Coli ◽  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cytochrome P450 3A4

Roles of Cytochrome b5in the Oxidation of Testosterone and Nifedipine by Recombinant Cytochrome P450 3A4 and by Human Liver Microsomes

1996 ◽  
Vol 325 (2) ◽  
pp. 174-182 ◽  
Author(s):  
Hiroshi Yamazaki ◽  
Masami Nakano ◽  
Yoshio Imai ◽  
Yune-Fang Ueng ◽  
F.Peter Guengerich ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cytochrome P450 3A4
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