PRP4 (RNA4) from Saccharomyces cerevisiae: its gene product is associated with the U4/U6 small nuclear ribonucleoprotein particle.
1989 ◽
Vol 9
(9)
◽
pp. 3698-3709
◽
Keyword(s):
The PRP4 (RNA4) gene product is involved in nuclear mRNA processing in yeast cells; we have previously cloned the gene by complementation of a temperature-sensitive mutation. Sequence and transcript analyses of the cloned gene predicted the gene product to be a 52-kilodalton protein, which was confirmed with antibodies raised against the PRP4 gene product. These antibodies inhibited precursor mRNA splicing in vitro, demonstrating a direct role of PRP4 in splicing. Immunoprecipitations with the antibodies indicated that the PRP4 protein is associated with the U4/U6 small nuclear ribonucleoprotein particle.
1993 ◽
Vol 13
(5)
◽
pp. 2959-2970
1990 ◽
Vol 10
(12)
◽
pp. 6417-6425
◽
1993 ◽
Vol 13
(5)
◽
pp. 2959-2970
◽
1996 ◽
Vol 16
(3)
◽
pp. 960-967
◽
1990 ◽
Vol 10
(12)
◽
pp. 6417-6425
Uncoupling two functions of the U1 small nuclear ribonucleoprotein particle during in vitro splicing
1993 ◽
Vol 13
(6)
◽
pp. 3135-3145
1993 ◽
Vol 13
(6)
◽
pp. 3135-3145
◽
1987 ◽
Vol 7
(11)
◽
pp. 4030-4037
◽