Synthesis of blood serum thymic factor and its analogs

1986 ◽  
Vol 51 (12) ◽  
pp. 2909-2918 ◽  
Author(s):  
Martin Černý ◽  
Evžen Kasafírek ◽  
Jozef Rovenský ◽  
Jiří Křepelka
Keyword(s):  
Biological Activity ◽  
Blood Serum ◽  
Inhibitory Effect ◽  
Serum Thymic Factor ◽  
Thymic Factor

The blood serum thymic factor (FTS) and its two analogs (desGlp1)-FTS and (Gln1)-FTS were synthesized by a novel procedure. The biological activity of these compounds was assayed by the E-rosette test. The activity of (desGlp1)-FTS is decreased and (Gln1)-FTS shows an inhibitory effect.

Biological activity of synthetic analogs of serum thymic factor*

2009 ◽  
Vol 21 (2) ◽  
pp. 135-144 ◽  
Author(s):  
JUNICHIRO GYOTOKU ◽  
AKIRA IMAIZUMI ◽  
SHIGEYUKI TERADA ◽  
EIJI KIMOTO
Keyword(s):  
Biological Activity ◽  
Synthetic Analogs ◽  
Serum Thymic Factor ◽  
Thymic Factor

scholarly journals Structural requirement for the biological activity of serum thymic factor

FEBS Letters ◽  
1981 ◽  
Vol 128 (1) ◽  
pp. 108-110 ◽  
Author(s):  
Akira Imaizumi ◽  
Junichiro Gyotoku ◽  
Shigeyuki Terada ◽  
Eiji Kimoto
Keyword(s):  
Biological Activity ◽  
Structural Requirement ◽  
Serum Thymic Factor ◽  
Thymic Factor

scholarly journals Contribution of zinc and other metals to the biological activity of the serum thymic factor.

1982 ◽  
Vol 79 (17) ◽  
pp. 5370-5373 ◽  
Author(s):  
M. Dardenne ◽  
J. M. Pleau ◽  
B. Nabarra ◽  
P. Lefrancier ◽  
M. Derrien ◽  
...  
Keyword(s):  
Biological Activity ◽  
Serum Thymic Factor ◽  
Thymic Factor

Role of zinc and other metals in the biological activity of serum thymic factor (FTS)

1982 ◽  
Vol 4 (4) ◽  
pp. 298
Author(s):  
M. Dardenne ◽  
J.M. Pléau ◽  
B. Nabarra ◽  
P. Lefrancier ◽  
M. Derrien ◽  
...  
Keyword(s):  
Biological Activity ◽  
Serum Thymic Factor ◽  
Thymic Factor

ChemInform Abstract: Synthesis of Blood Serum Thymic Factor and Its Analogs.

ChemInform ◽  
1987 ◽  
Vol 18 (18) ◽  
Author(s):  
M. CERNY ◽  
E. KASAFIREK ◽  
J. ROVENSKY ◽  
J. KREPELKA
Keyword(s):  
Blood Serum ◽  
Serum Thymic Factor ◽  
Thymic Factor

scholarly journals Synthesis and Evaluation of Biological Activity of New Arylphosphoramidates

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Amal Thebti ◽  
M. A. K. Sanhoury ◽  
H-I. Ouzari ◽  
T. Barhoumi-slimi
Keyword(s):  
Biological Activity ◽  
Ir Spectroscopy ◽  
Acetylcholinesterase Activity ◽  
Inhibitory Effect ◽  
Bacterial Strains ◽  
Significant Inhibitory Effect ◽  
Subsequent Addition

The synthesis of new substituted arylphosphoramidates is performed in two steps through phosphorylation of the corresponding alcohols followed by aminolysis. The formation of the desired phosphoramidates depends on the subsequent addition of the two alcohols with the amine being added at the last step. The products were obtained in 58–95% yields. They were characterized mainly by multinuclear (1H, 13C, 31P, and 19F) NMR and IR spectroscopy. In addition, the antimicrobial and antiacetylcholinesterase activities were evaluated. The results showed acetylcholinesterase activity by some compounds, whilst no significant inhibitory effect against the tested bacterial strains has been recorded.

Specificity of Metal Binding to Serum Thymic Factor (FTS)

1984 ◽  
pp. 31-34
Author(s):  
L.N. GASTINEL ◽  
M. DARDENNE ◽  
J.M. PLEAU ◽  
J.F. BACH
Keyword(s):  
Metal Binding ◽  
Serum Thymic Factor ◽  
Thymic Factor
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