scholarly journals Immunogenicity of routine vaccination against diphtheria, tetanus, and Haemophilus influenzae type b in Asian infants born in the United Kingdom

2005 ◽  
Vol 90 (6) ◽  
pp. 589-591 ◽  
Author(s):  
R Booy
Keyword(s):  
United Kingdom ◽  
Haemophilus Influenzae ◽  
Routine Vaccination ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B ◽  
The United Kingdom

scholarly journals Haemophilus influenzae type b conjugate vaccine trial in Oxford: implications for the United Kingdom.

1989 ◽  
Vol 64 (4) ◽  
pp. 520-524 ◽  
Author(s):  
G Tudor-Williams ◽  
J Frankland ◽  
D Isaacs ◽  
R T Mayon-White ◽  
J A MacFarlane ◽  
...  
Keyword(s):  
United Kingdom ◽  
Haemophilus Influenzae ◽  
Conjugate Vaccine ◽  
Vaccine Trial ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B ◽  
The United Kingdom

Epidemiology of Haemophilus Type B Invasive Disease in Childhood in Glasgow

1993 ◽  
Vol 38 (1) ◽  
pp. 18-20 ◽  
Author(s):  
A Coggins ◽  
C.W. Shepherd ◽  
F. Cockburn
Keyword(s):  
Haemophilus Influenzae ◽  
Invasive Disease ◽  
Annual Incidence ◽  
Childhood Vaccination ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B ◽  
Neurological Sequelae ◽  
The United Kingdom

The objective of this study was to investigate the epidemiology of invasive disease due to Haemophilus influenzae type b in childhood in Glasgow. A retrospective study has been made on the hospital records of 252 children aged 0 to 12 years admitted to Glasgow hospitals during 1981–1990. The annual incidence of invasive Haemophilus influenzae type b disease in Glasgow was estimated at 39 per 100,000 children less than five years of age per year. The figure for Haemophilus meningitis was 23.8 per 100,000 children less than five years of age per year. Ninety-five per cent of all cases occurred in children less than five years of age and 72.1% of meningitis cases occurred before two years of age. There was a mortality of 2.77%. Long-term neurological sequelae were found in 15.3% of the survivors. The annual incidence of Haemophilus influenzae type b disease is slightly higher in Glasgow than previously reported for the United Kingdom. The study provides baseline data to help assess efficacy of proposed early childhood vaccination.

scholarly journals Impact of routine vaccination against Haemophilus influenzae type b in The Gambia: 20 years after its introduction

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Syed MA Zaman ◽  
Stephen RC Howie ◽  
Magnus Ochoge ◽  
Ousman Secka ◽  
Alasana Bah ◽  
...  
Keyword(s):  
Haemophilus Influenzae ◽  
The Gambia ◽  
Routine Vaccination ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B

scholarly journals Long-term impact of vaccination on Haemophilus influenzae type b (Hib) carriage in the United Kingdom

2004 ◽  
Vol 132 (4) ◽  
pp. 765-767 ◽  
Author(s):  
J. McVERNON ◽  
A. J. HOWARD ◽  
M. P. E. SLACK ◽  
M. E. RAMSAY
Keyword(s):  
United Kingdom ◽  
Haemophilus Influenzae ◽  
Invasive Disease ◽  
Haemophilus Influenzae Type ◽  
Type B ◽  
Cross Sectional ◽  
Laboratory Service ◽  
Vaccine Introduction ◽  
The United Kingdom ◽  
Long Term Impact

A recent resurgence in serious infections due to Haemophilus influenzae type b (Hib) has been observed in the United Kingdom. More information on Hib transmission in the population is required in order to better understand the mechanism of this increase. The Public Health Laboratory Service (subsumed into the Health Protection Agency since April 2004) conducted four cross-sectional studies of asymptomatic oropharyngeal Hib carriage in children attending day-care nurseries in England and Wales in 1992, 1994, 1997 and 2002. These demonstrated a marked reduction in the prevalence of Hib colonization over time since vaccine introduction (3·98% in 1992; 0·70% in 1994; 0% in 1997; 0% in 2002), which did not explain the increase in invasive disease reports from 1999 onwards. We believe that a reduction in antibody levels over the first 5 years of life in immunized children in recent years has fuelled the rise in reported cases in the absence of an obvious increase in transmission.

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