THU0416 Disease Activity and Safety During Long-Term (104-Week) Treatment with Apremilast, An Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis: Results from a Phase III, Randomized, Controlled Trial and Open-Label Extension (Palace 3)

C. Edwards; F. Blanco; J. Crowley; C. Hu; K. Shah; C. Birbara

doi:10.1136/annrheumdis-2015-eular.2889

THU0416 Disease Activity and Safety During Long-Term (104-Week) Treatment with Apremilast, An Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis: Results from a Phase III, Randomized, Controlled Trial and Open-Label Extension (Palace 3)

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2015-eular.2889 ◽

2015 ◽

Vol 74 (Suppl 2) ◽

pp. 348.2-349 ◽

Cited By ~ 3

Author(s):

C. Edwards ◽

F. Blanco ◽

J. Crowley ◽

C. Hu ◽

K. Shah ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Psoriatic Arthritis ◽

Controlled Trial ◽

Phase Iii ◽

Open Label ◽

Phosphodiesterase 4 ◽

Randomized Controlled ◽

Open Label Extension ◽

Phosphodiesterase 4 Inhibitor

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FRI0447 Long-Term (156-Week) Efficacy and Safety Profile of Apremilast, An Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis: Results from A Phase III, Randomized, Controlled Trial and Open-Label Extension (Palace 1)

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2016-eular.3256 ◽

2016 ◽

Vol 75 (Suppl 2) ◽

pp. 597.2-598

Author(s):

A. Kavanaugh ◽

D.D. Gladman ◽

J.J. Gomez-Reino ◽

S. Hall ◽

E. Lespessailles ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Controlled Trial ◽

Phase Iii ◽

Efficacy And Safety ◽

Open Label ◽

Phosphodiesterase 4 ◽

Randomized Controlled ◽

Open Label Extension ◽

Phosphodiesterase 4 Inhibitor

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217. Long-Term (104-Week) Efficacy and Safety Profile of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis: Results from a Phase III, Randomized, Controlled Trial and Open-Label Extension (PALACE 1)

Rheumatology ◽

10.1093/rheumatology/kev089.104 ◽

2015 ◽

Keyword(s):

Randomized Controlled Trial ◽

Controlled Trial ◽

Phase Iii ◽

Efficacy And Safety ◽

Open Label ◽

Phosphodiesterase 4 ◽

Randomized Controlled ◽

Open Label Extension ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

Efficacy of long-term (104-week) treatment with apremilast in patients with psoriatic arthritis: Results from a phase III, randomized, controlled trial and open-label extension

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2016.02.968 ◽

2016 ◽

Vol 74 (5) ◽

pp. AB248

Keyword(s):

Randomized Controlled Trial ◽

Psoriatic Arthritis ◽

Controlled Trial ◽

Phase Iii ◽

Open Label ◽

Randomized Controlled ◽

Open Label Extension

Download Full-text

THU0420 Long-Term (104-Week) Efficacy and Safety Profile of Apremilast, An Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis: Results from a Phase III, Randomised, Controlled Trial and Open-Label Extension (Palace 1)

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2015-eular.2907 ◽

2015 ◽

Vol 74 (Suppl 2) ◽

pp. 350.2-351 ◽

Cited By ~ 2

Author(s):

A. Kavanaugh ◽

A. Adebajo ◽

D. Gladman ◽

J. Gomez-Reino ◽

S. Hall ◽

...

Keyword(s):

Psoriatic Arthritis ◽

Controlled Trial ◽

Phase Iii ◽

Efficacy And Safety ◽

Open Label ◽

Phosphodiesterase 4 ◽

Open Label Extension ◽

Randomised Controlled ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

LB0001 Long-Term (52-Week) Results of a Phase 3, Randomized, Controlled Trial of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2013-eular.526 ◽

2013 ◽

Vol 72 (Suppl 3) ◽

pp. A163-A163 ◽

Cited By ~ 5

Author(s):

A. Kavanaugh ◽

P. J. Mease ◽

A. O. Adebajo ◽

J. Wollenhaupt ◽

C. Hu ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Psoriatic Arthritis ◽

Controlled Trial ◽

Phase 3 ◽

Phosphodiesterase 4 ◽

Randomized Controlled ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

SAT0377 Long-Term Safety and Tolerability of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis: A Phase 3, Randomized, Controlled Trial

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2014-eular.1575 ◽

2014 ◽

Vol 73 (Suppl 2) ◽

pp. 730.2-730 ◽

Cited By ~ 1

Author(s):

A. Adebajo ◽

A. Wells ◽

C. Edwards ◽

A. Kivitz ◽

P. Bird ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Psoriatic Arthritis ◽

Controlled Trial ◽

Phase 3 ◽

Phosphodiesterase 4 ◽

Randomized Controlled ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

Long-term safety and tolerability of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with moderate to severe psoriasis: Results from a phase III, randomized, controlled trial (ESTEEM 1)

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2014.01.722 ◽

2014 ◽

Vol 70 (5) ◽

pp. AB174 ◽

Cited By ~ 1

Keyword(s):

Randomized Controlled Trial ◽

Controlled Trial ◽

Severe Psoriasis ◽

Phase Iii ◽

Phosphodiesterase 4 ◽

Randomized Controlled ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

SAT0382 Palace 4, A Phase 3, Randomized, Controlled TRIAL of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, for Treatment of Psoriatic Arthritis: Long-Term (52-WEEK) Improvements in Physical Function

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2014-eular.1096 ◽

2014 ◽

Vol 73 (Suppl 2) ◽

pp. 732.1-732 ◽

Cited By ~ 1

Author(s):

A. Wells ◽

C. Edwards ◽

A.O. Adebajo ◽

A.J. Kivitz ◽

P. Bird ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Psoriatic Arthritis ◽

Physical Function ◽

Controlled Trial ◽

Phase 3 ◽

Phosphodiesterase 4 ◽

Randomized Controlled ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

212. Long-Term 52-Week Results of Palace 3, A Phase 3, Randomized, Controlled Trial of Apremilast, An Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis and Current Skin Involvement

Rheumatology ◽

10.1093/rheumatology/keu115.006 ◽

2014 ◽

Vol 53 (suppl_1) ◽

pp. i138-i139 ◽

Cited By ~ 8

Author(s):

Christopher J. Edwards ◽

Francisco J. Blanco ◽

Jeffrey Crowley ◽

ChiaChi Hu ◽

Randall M. Stevens ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Psoriatic Arthritis ◽

Controlled Trial ◽

Skin Involvement ◽

Phase 3 ◽

Phosphodiesterase 4 ◽

Randomized Controlled ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

SAT0389 Apremilast, an Oral Phosphodiesterase 4 Inhibitor, is Associated with Long-Term (52-Week) Improvements in Enthesitis and Dactylitis in Patients with Psoriatic Arthritis: Results from the Palace 4 Phase 3, Randomized, Controlled Trial

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2014-eular.1574 ◽

2014 ◽

Vol 73 (Suppl 2) ◽

pp. 735.1-735 ◽

Cited By ~ 5

Author(s):

C. Edwards ◽

A. Wells ◽

A. Adebajo ◽

A. Kivitz ◽

P. Bird ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Psoriatic Arthritis ◽

Controlled Trial ◽

Phase 3 ◽

Phosphodiesterase 4 ◽

Randomized Controlled ◽

Phosphodiesterase 4 Inhibitor

Download Full-text