scholarly journals Acute abdominal pain in systemic lupus erythematosus: factors contributing to recurrence of lupus enteritis

2006 ◽  
Vol 65 (11) ◽  
pp. 1537-1538 ◽  
Author(s):  
Y G Kim ◽  
H K Ha ◽  
S S Nah ◽  
C-K Lee ◽  
H-B Moon ◽  
...  
2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S64-S64 ◽  
Author(s):  
Hany Meawad ◽  
Andrew Kobalka ◽  
Yaseen Alastal ◽  
Brooke Koltz

Abstract Objectives Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease that can show wide manifestations in many organs. The gastrointestinal tract (GI) is commonly affected in SLE; symptoms are often related to the side effect of medications or to infections. One rare GI complication of SLE is lupus enteritis, a complex of manifestations including intestinal vasculitis and enteric ischemia, which presents with vague symptoms of severe abdominal pain, nausea, vomiting, and diarrhea. Methods We present the case of a 25-year-old female who was admitted to the hospital with complaints of abdominal pain, vomiting, diarrhea, and a history of SLE. Complicating the patient’s clinical picture and diagnosis was gastrointestinal bleeding requiring multiple blood product transfusions secondary to bleeding Meckel’s diverticulum, lupus flare, and positive stool culture for campylobacter antigen. Repeated upper and lower GI endoscopies with biopsy failed to identify the exact cause of bleeding and GI symptoms; the patient underwent exploratory laparotomy with right hemicolectomy to control bleeding. Microscopic examination revealed marked small vessel acute vasculitis consistent with lupus enteritis, ischemic enteritis, and Meckel’s diverticulum with gastric heterotopia. Results Our patient was subsequently aggressively treated; however, she developed further associated complications and died. Conclusion The pathologic diagnosis of lupus enteritis is challenging due to the nonspecific clinical symptoms and paucity of pathologic findings on most biopsy specimens. Lupus enteritis must be considered in the differential diagnosis of severe abdominal pain in lupus patients to aid in early diagnosis and treatment as this condition could be severe and potentially fatal.


2018 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Eunjee Lee ◽  
Min-Kyung Yeo ◽  
Sun kyoung You ◽  
Yeo Koon Kim ◽  
Seung Ryu ◽  
...  

2012 ◽  
Vol 75 (6) ◽  
pp. 1267-1268 ◽  
Author(s):  
Raj Majithia ◽  
Grishma Joy ◽  
John Liang ◽  
Kevin Olden

2019 ◽  
Vol 42 (2) ◽  
pp. 108-110
Author(s):  
Marta Gravito-Soares ◽  
Elisa Gravito-Soares ◽  
Manuela Ferreira ◽  
Luis Tomé

2010 ◽  
Vol 27 (12) ◽  
pp. 964-964
Author(s):  
Y.-C. Wu ◽  
H.-L. Kuo ◽  
C.-H. Kao ◽  
T.-C. Hsieh ◽  
K.-Y. Yen ◽  
...  

2017 ◽  
Vol 08 (03) ◽  
pp. 134-136 ◽  
Author(s):  
Vishal Bodh ◽  
Ritesh Kalwar ◽  
Rajesh Sharma ◽  
Brij Sharma ◽  
Sanjay Mahajan ◽  
...  

ABSTRACTSystemic lupus erythematosus (SLE) is an autoimmune disorder generally affects young to middle-aged women, commonly presenting as a triad of fever, rash, and joint pain but can affect multiple organs and can present in a complex fashion, varying based on the degree and severity of organ involvement. The differential for abdominal pain and diarrhea in SLE is vast and can include VIPomas, serositis, pancreatitis, intestinal vasculitis, and protein – losing enteropathy, gluten – enteropathy, intestinal pseudo-obstruction, and infection. The pathology of lupus enterits thought to be immune-complex deposition and complement activation, with subsequent mucosal edema. We present a case of a woman with no history of SLE, but with a prolonged course of abdominal pain, diarrhoea and vomiting and eventual diagnoses of lupus enteritis.


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