scholarly journals Rapid evolution from "normal" left ventricular outflow tract to fatal subaortic stenosis in infancy.

Heart ◽  
1981 ◽  
Vol 45 (5) ◽  
pp. 605-609 ◽  
Author(s):  
R M Freedom ◽  
R S Fowler ◽  
W J Duncan
2012 ◽  
Vol 50 (No. 7) ◽  
pp. 321-326
Author(s):  
J. Pikula ◽  
J. Pikulova ◽  
H. Bandouchova ◽  
P. Kohout ◽  
K. Najman ◽  
...  

A combined congenital heart defect of aortic stenosis and mitral dysplasia was diagnosed in three Black Russian Terrier puppies two months old. The aortic stenosis component included both fixed and dynamic obstructions. The fixed obstruction was subvalvularly located at the entrance to the left ventricular outflow tract. The dynamic obstruction was caused by the septal leaflet of the mitral valve protruding into the left ventricular outflow tract. Mitral dysplasia resulted in mitral insufficiency leading to regurgitation through the mitral valve closer to the septal side. The maximum pressure gradient across the aortic valve amounting to 103 mmHg measured in one puppy was consistent with the most severe grade of stenosis. The diagnosis was confirmed by autopsy in all three puppies that were males and originated in one litter, so genetic influences are supposed.


2006 ◽  
Vol 29 (9) ◽  
pp. 421-421 ◽  
Author(s):  
Hau-De Lin ◽  
Pai-Feng Hsu ◽  
Mei-Han Wu ◽  
Hsin-Bang Leu ◽  
Tsui-Lieh Hsu

1994 ◽  
Vol 4 (3) ◽  
pp. 307-309
Author(s):  
Abraham Lorber ◽  
D. Itzkovitch ◽  
F. Hallon

SummaryA 43-year-old female with complaints of exertional dyspnea was found by Doppler echocardiography to have fixed subaortic stenosis and a redundant mitral valve which, during systole, formed a chamber in the left ventricular outflow tract. This resulted in a subaortic gradient of 40 mm Hg. There was also moderate aortic regurgitation.


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