Spatiotemporal characteristics of surround suppression in primary visual cortex and lateral geniculate nucleus of the cat

2014 ◽  
Vol 112 (3) ◽  
pp. 603-619 ◽  
Author(s):  
Satoshi Shimegi ◽  
Ayako Ishikawa ◽  
Hiroyuki Kida ◽  
Hiroshi Sakamoto ◽  
Sin-ichiro Hara ◽  
...  
Keyword(s):  
Visual Cortex ◽  
Receptive Field ◽  
Lateral Geniculate Nucleus ◽  
Primary Visual Cortex ◽  
Neuronal Response ◽  
High Specificity ◽  
Fast Component ◽  
Sinusoidal Grating ◽  
Temporal Properties ◽  
Lateral Geniculate

In the primary visual cortex (V1), a neuronal response to stimulation of the classical receptive field (CRF) is predominantly suppressed by a stimulus presented outside the CRF (extraclassical receptive field, ECRF), a phenomenon referred to as ECRF suppression. To elucidate the neuronal mechanisms and origin of ECRF suppression in V1 of anesthetized cats, we examined the temporal properties of the spatial extent and orientation specificity of ECRF suppression in V1 and the lateral geniculate nucleus (LGN), using stationary-flashed sinusoidal grating. In V1, we found three components of ECRF suppression: 1) local and fast, 2) global and fast, and 3) global and late. The local and fast component, which resulted from within 2° of the boundary of the CRF, started no more than 10 ms after the onset of the CRF response and exhibited low specificity for the orientation of the ECRF stimulus. These spatiotemporal properties corresponded to those of geniculate ECRF suppression, suggesting that the local and fast component of V1 is inherited from the LGN. In contrast, the two global components showed rather large spatial extents ∼5° from the CRF boundary and high specificity for orientation, suggesting that their possible origin is the cortex, not the LGN. Correspondingly, the local component was observed in all neurons of the thalamocortical recipient layer, while the global component was biased toward other layers. Therefore, we conclude that both subcortical and cortical mechanisms with different spatiotemporal properties are involved in ECRF suppression.

scholarly journals Elastic Net Model of Ocular Dominance: Overall Stripe Pattern and Monocular Deprivation

1994 ◽  
Vol 6 (4) ◽  
pp. 615-621 ◽  
Author(s):  
Geoffrey J. Goodhill ◽  
David J. Willshaw
Keyword(s):  
Visual Cortex ◽  
Lateral Geniculate Nucleus ◽  
Primary Visual Cortex ◽  
Ocular Dominance ◽  
Monocular Deprivation ◽  
Elastic Net ◽  
Global Order ◽  
Stripe Pattern ◽  
Lateral Geniculate ◽  
Stripe Width

The elastic net (Durbin and Willshaw 1987) can account for the development of both topography and ocular dominance in the mapping from the lateral geniculate nucleus to primary visual cortex (Goodhill and Willshaw 1990). Here it is further shown for this model that (1) the overall pattern of stripes produced is strongly influenced by the shape of the cortex: in particular, stripes with a global order similar to that seen biologically can be produced under appropriate conditions, and (2) the observed changes in stripe width associated with monocular deprivation are reproduced in the model.

Distribution of neurofilament proteins in the lateral geniculate nucleus, primary visual cortex, and area MT of adultCebus monkeys

2008 ◽  
Vol 508 (4) ◽  
pp. 605-614 ◽  
Author(s):  
Juliana Guimarães Martins Soares ◽  
Paulo Henrique Rosado De Castro ◽  
Mario Fiorani ◽  
Sheila Nascimento-Silva ◽  
Ricardo Gattass
Keyword(s):  
Visual Cortex ◽  
Lateral Geniculate Nucleus ◽  
Primary Visual Cortex ◽  
Neurofilament Proteins ◽  
Area Mt ◽  
Lateral Geniculate

Numerical relationship between neurons in the lateral geniculate nucleus and primary visual cortex in macaque monkeys

1996 ◽  
Vol 13 (3) ◽  
pp. 585-590 ◽  
Author(s):  
Ivan Suner ◽  
Pasko Rakic
Keyword(s):  
Visual Cortex ◽  
Lateral Geniculate Nucleus ◽  
Primary Visual Cortex ◽  
Rhesus Monkeys ◽  
Three Dimensional ◽  
Area 17 ◽  
Counting Method ◽  
Lateral Geniculate ◽  
Cortex Area ◽  
The Right

AbstractWe examined the numerical correlation between total populations of neurons in the lateral geniculate nucleus (LGN) and the primary visual cortex (area 17 of Brodmann) in ten cerebral hemispheres of five normal rhesus monkeys using an unbiased three-dimensional counting method. There were 1.4 ± 0.2 million and 341 ±54 million neurons in the LGN and area 17, respectively. In each animal, a larger LGN on one side was in register with a larger area 17 of the cortex on the same side. Furthermore, asymmetry in the number of neurons in both the LGN and area 17 favored the right side. However, because of small variations across subjects, correlation between the total neuron number in LGN and area 17 was weak (r = 0.29). These results suggest that the final numbers of neurons in these visual centers may be established independently or by multiple factors controlling elimination of initially overproduced neurons.

Spatial Distribution of Suppressive Signals Outside the Classical Receptive Field in Lateral Geniculate Nucleus

2005 ◽  
Vol 94 (3) ◽  
pp. 1789-1797 ◽  
Author(s):  
Ben S. Webb ◽  
Christopher J. Tinsley ◽  
Christopher J. Vincent ◽  
Andrew M. Derrington
Keyword(s):  
Spatial Distribution ◽  
Receptive Field ◽  
Lateral Geniculate Nucleus ◽  
Spatial Organization ◽  
Temporal Frequency ◽  
Spatial Summation ◽  
Sinusoidal Grating ◽  
Circular Symmetry ◽  
Lateral Geniculate ◽  
Classical Receptive Field

A suppressive surround modulates the responsiveness of cells in the lateral geniculate nucleus (LGN), but we know nothing of its spatial structure or the way in which it combines signals arising from different locations. It is generally assumed that suppressive signals are either uniformly distributed or balanced in opposing regions outside the receptive field. Here, we examine the spatial distribution and summation of suppressive signals outside the receptive field in extracellular recordings from 46 LGN cells in anesthetized marmosets. The receptive field of each cell was stimulated with a drifting sinusoidal grating of the preferred size and spatial and temporal frequency; we probed different positions in the suppressive surround with either a large half-annular grating or a small circular grating patch of the preferred spatial and temporal frequency. In many of the cells with a strong suppressive surround (29/46), the spatial distribution of suppression showed clear deviation from circular symmetry. In the majority of these of cells, suppressive signals were spatially asymmetrical or balanced in opposing areas outside the receptive field. A suppressive area was larger than the classical receptive field itself and spatial summation within and between these areas was nonlinear. There was no bias for suppression to arise from foveal or nasal retina where cone density is higher and no other sign of a systematic spatial organization to the suppressive surround. We conclude that nonclassical suppressive signals in LGN deviate from circular symmetry and are nonlinearly combined.

Sign in / Sign up

Export Citation Format

Share Document