scholarly journals A Case of Rathke’s Cleft Cyst Associated with Transient Central Adrenal Insufficiency and Masked Diabetes Insipidus

2014 ◽  
Vol 2014 ◽  
pp. 1-6
Author(s):  
Masahiro Asakawa ◽  
Rina Chin ◽  
Yoshihiro Niitsu ◽  
Tetsuo Sekine ◽  
Arisa Niwa ◽  
...  

A 73-year-old woman admitted to our hospital because of headache, poor appetite, malaise, weight loss, and vomiting was found to have central adrenal insufficiency and thyrotoxicosis due to silent thyroiditis. Polyuria developed after replacement with glucocorticoid (masked diabetes insipidus), which was controlled with nasal administration of desmopressin. Magnetic resonance imaging of the brain showed a large cystic pituitary mass (18 × 18 × 12 mm) extending suprasellarly to the optic chiasm. Transsphenoidal surgery revealed that the pituitary tumor was Rathke’s cleft cyst. Following surgery, replacement with neither glucocorticoid nor desmopressin was needed any more. Therefore, it is suggested that Rathke’s cleft cyst is responsible for the masked diabetes insipidus and the central insufficiency. Furthermore, it is speculated that thyrotoxicosis with painless thyroiditis might induce changes from subclinical adrenal insufficiency to transiently overt insufficiency.

2000 ◽  
Vol 47 (4) ◽  
pp. 393-399 ◽  
Author(s):  
HIROSHI IWAI ◽  
YASUHIRO OHNO ◽  
MADOKA HOSHIRO ◽  
MIKA FUJIMOTO ◽  
AKIYOSHI NISHIMURA ◽  
...  

1999 ◽  
Vol 46 (1) ◽  
pp. 187-192 ◽  
Author(s):  
SEIJI HAMA ◽  
KAZUNORI ARITA ◽  
ATSUSHI TOMINAGA ◽  
MASAMI YOSHIKAWA ◽  
KUNIKI EGUCHI ◽  
...  

2015 ◽  
Vol 54 (8) ◽  
pp. 935-940
Author(s):  
Tomoko Asano ◽  
Hodaka Yamada ◽  
Masashi Yoshida ◽  
Atsushi Aoki ◽  
Aki Ikoma ◽  
...  

2012 ◽  
Vol 51 (2) ◽  
pp. 189-194 ◽  
Author(s):  
Tomoko Asano ◽  
Atsushi Aoki ◽  
Masami Sasaki ◽  
Aki Ikoma ◽  
Hideo Toyoshima ◽  
...  

2017 ◽  
Vol 15 (1) ◽  
pp. 23
Author(s):  
Ha Yeon Kim ◽  
Seung Jin Lee ◽  
Eun Hui Bae ◽  
Seong Kwon Ma ◽  
Soo Wan Kim

Neurosurgery ◽  
2005 ◽  
Vol 56 (1) ◽  
pp. 124-129 ◽  
Author(s):  
Giorgio Frank ◽  
Vittorio Sciarretta ◽  
Diego Mazzatenta ◽  
Giovanni Farneti ◽  
Giovanni Carlo Modugno ◽  
...  

Abstract OBJECTIVE: In this study, the usefulness of the transsphenoidal endoscopic approach in the treatment of a Rathke's cleft cyst is reported. METHODS: Between June 1998 and December 2002, 22 patients affected by sellar-suprasellar Rathke's cleft cysts were treated using a transsphenoidal endoscopic approach. Fourteen patients experienced pituitary dysfunction (64%), five experienced visual impairment (23%), and three reported headaches (14%). RESULTS: The patient follow-up ranged from 8 to 60 months (mean, 33 mo). Pituitary function was restored only in the four patients with hyperprolactinemia, whereas visual impairment and headache improved in all patients. However, when present before surgery, hypopituitarism was unaffected by surgery. Two patients experienced permanent diabetes insipidus (one of them before surgery). Only one recurrence was observed in a 13-year-old girl at 12 months after surgery, and it was treated using a new transsphenoidal endoscopic approach. CONCLUSION: The transsphenoidal endoscopic approach represents a straightforward and mini-invasive approach for the drainage and biopsy of a Rathke's cleft cyst.


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