scholarly journals Hypothalamic Type of Hypopituitarism and Central Diabetes Insipidus Probably Linked to Rathke's Cleft Cyst

2015 ◽  
Vol 54 (8) ◽  
pp. 935-940
Author(s):  
Tomoko Asano ◽  
Hodaka Yamada ◽  
Masashi Yoshida ◽  
Atsushi Aoki ◽  
Aki Ikoma ◽  
...  
1999 ◽  
Vol 46 (1) ◽  
pp. 187-192 ◽  
Author(s):  
SEIJI HAMA ◽  
KAZUNORI ARITA ◽  
ATSUSHI TOMINAGA ◽  
MASAMI YOSHIKAWA ◽  
KUNIKI EGUCHI ◽  
...  

2012 ◽  
Vol 51 (2) ◽  
pp. 189-194 ◽  
Author(s):  
Tomoko Asano ◽  
Atsushi Aoki ◽  
Masami Sasaki ◽  
Aki Ikoma ◽  
Hideo Toyoshima ◽  
...  

2017 ◽  
Vol 15 (1) ◽  
pp. 23
Author(s):  
Ha Yeon Kim ◽  
Seung Jin Lee ◽  
Eun Hui Bae ◽  
Seong Kwon Ma ◽  
Soo Wan Kim

2014 ◽  
Vol 2014 ◽  
pp. 1-6
Author(s):  
Masahiro Asakawa ◽  
Rina Chin ◽  
Yoshihiro Niitsu ◽  
Tetsuo Sekine ◽  
Arisa Niwa ◽  
...  

A 73-year-old woman admitted to our hospital because of headache, poor appetite, malaise, weight loss, and vomiting was found to have central adrenal insufficiency and thyrotoxicosis due to silent thyroiditis. Polyuria developed after replacement with glucocorticoid (masked diabetes insipidus), which was controlled with nasal administration of desmopressin. Magnetic resonance imaging of the brain showed a large cystic pituitary mass (18 × 18 × 12 mm) extending suprasellarly to the optic chiasm. Transsphenoidal surgery revealed that the pituitary tumor was Rathke’s cleft cyst. Following surgery, replacement with neither glucocorticoid nor desmopressin was needed any more. Therefore, it is suggested that Rathke’s cleft cyst is responsible for the masked diabetes insipidus and the central insufficiency. Furthermore, it is speculated that thyrotoxicosis with painless thyroiditis might induce changes from subclinical adrenal insufficiency to transiently overt insufficiency.


Neurosurgery ◽  
2005 ◽  
Vol 56 (1) ◽  
pp. 124-129 ◽  
Author(s):  
Giorgio Frank ◽  
Vittorio Sciarretta ◽  
Diego Mazzatenta ◽  
Giovanni Farneti ◽  
Giovanni Carlo Modugno ◽  
...  

Abstract OBJECTIVE: In this study, the usefulness of the transsphenoidal endoscopic approach in the treatment of a Rathke's cleft cyst is reported. METHODS: Between June 1998 and December 2002, 22 patients affected by sellar-suprasellar Rathke's cleft cysts were treated using a transsphenoidal endoscopic approach. Fourteen patients experienced pituitary dysfunction (64%), five experienced visual impairment (23%), and three reported headaches (14%). RESULTS: The patient follow-up ranged from 8 to 60 months (mean, 33 mo). Pituitary function was restored only in the four patients with hyperprolactinemia, whereas visual impairment and headache improved in all patients. However, when present before surgery, hypopituitarism was unaffected by surgery. Two patients experienced permanent diabetes insipidus (one of them before surgery). Only one recurrence was observed in a 13-year-old girl at 12 months after surgery, and it was treated using a new transsphenoidal endoscopic approach. CONCLUSION: The transsphenoidal endoscopic approach represents a straightforward and mini-invasive approach for the drainage and biopsy of a Rathke's cleft cyst.


2015 ◽  
Vol 21 (3) ◽  
pp. 137-140
Author(s):  
Ana Valea ◽  
Alexandra Marcusan ◽  
Mara Carsote ◽  
Adina Ghemigian ◽  
Cristina Ghervan ◽  
...  

ABSTRACT Introduction The Rathke cyst represents an unusual benign tumour derived from Rathke’s cleft remnants. The diagnosis is potential seen at any age. The most frequent signs are mostly mass effects as headache, visual field defects and hypopituitarism. Case presentation 30-year old female is admitted for persistent headache that was later associated with secondary amenorrhea and visual field defects for the last two years. The clinical data are consistent with high levels of serum prolactin, gonadotropes deficiency, as well as central hypothyroidism. The magnetic resonance imagery found a pituitary tumour of 2.7 centimetres with extrapituitary extension up to the optic chiasm. Surgery was performed in order to remove the tumour. The pathologic report confirmed a Rathke’s cleft cyst. Diabetes insipidus associated with panhypopituitarism was diagnosed and treated after the procedure. Close follow-up is necessary. Conclusion This case highlights the fact that headache sometimes embraces a severe neoplasia diagnosis and that the iatrogenic complications after surgery are lifelong care demanding


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