scholarly journals Coexistence of Cervical Leiomyosarcoma and Gastric-Type Adenocarcinoma In Situ with Extensive Extension to the Endometrium and Fallopian Tube

2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Ayako Ura ◽  
Kanako Ogura ◽  
Asumi Sakaguchi ◽  
Hiroko Onagi ◽  
Daiki Ogishima ◽  
...  

Cervical leiomyosarcoma is known to be rare from the previous reviews of a large number of malignant cervical tumors. The patient was a 66-year-old woman with irregular vaginal bleeding. She underwent modified radical hysterectomy and bilateral salpingooophorectomy. Histopathologically, we diagnosed the coexistence of uterine cervical leiomyosarcoma and cervical gastric-type adenocarcinoma in situ with endometrial lesions that had continuous and skip patterns and fallopian tubal lesions with a partial lesion. To the best of our knowledge, cases of synchronous leiomyosarcoma and cancers have not often been reported; only two cases of synchronous cervical leiomyosarcoma and cervical squamous cell carcinoma have been published. This case is the first presentation of coincidental primary cervical leiomyosarcoma and cervical gastric-type adenocarcinoma in situ. Additionally, we considered cervical gastric-type adenocarcinoma in situ with continuous lesions on the endometrium and skip lesions on the left fallopian tube.

2017 ◽  
Vol 41 (8) ◽  
pp. 1023-1033 ◽  
Author(s):  
Karen L. Talia ◽  
Colin J.R. Stewart ◽  
Brooke E. Howitt ◽  
Marisa R. Nucci ◽  
W. Glenn McCluggage

Pathology ◽  
2018 ◽  
Vol 50 ◽  
pp. S8
Author(s):  
Karen L. Talia ◽  
Colin J.R. Stewart ◽  
Brooke E. Howitt ◽  
Marisa R. Nucci ◽  
W. Glenn McCluggage

2021 ◽  
Author(s):  
Nasim Shokouhi ◽  
Sara Saeedi ◽  
Soheila Sarmadi ◽  
Behnaz Moradi ◽  
Elham Feizabad

Abstract Background: Primary carcinoma of fallopian tube is a rare but deadly gynecologic cancer, In addition, its preoperative diagnosis is strict due to the lack of specific symptoms and signs and in most patients, it is an intraoperative finding.Case presentation: A 55-year-old patient, G3Ab1P2 referred to urogynecology clinic of our hospital with chief complaint about heavy, prolonged menstrual bleeding and a permanently abnormal yellow discharge that could not be distinguished from its urinary or vaginal source.After complete diagnostic work-up, the patient became a candidate for hysterectomy due to the drug (Megestrol Acetate) -resistant abnormal vaginal bleeding, her abnormal vaginal bleeding, positive family history of malignancy, and abnormal vaginal discharge.Laparotomy revealed unusual left fallopian tube feature (Large, bulky, and vegetative feature), suspected to malignancy. Intraoperative frozen-section analysis of the left fallopian tube and ovary specimens detected the mass as a high-grade serous carcinoma of fallopian tube. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, and partial omentectomy were performed. The definitive histopathological diagnosis was high-grade serous carcinoma of the left fallopian tube stage 2b with omental involvement without any evidence of lymph-vascular invasion.Conclusions: High-grade serous carcinoma of fallopian tube is likely to present nonspecific symptoms, which may cause considerable delay in diagnosis and treatment. This consequently, affects the prognosis and survival of the patient.


Cytopathology ◽  
2018 ◽  
Vol 30 (2) ◽  
pp. 265-267
Author(s):  
Amos Tay ◽  
Mihir Gudi ◽  
Timothy Yong Kuie Lim ◽  
Wu Bing Cheng ◽  
Joyce S. L. Tan ◽  
...  

2020 ◽  
Author(s):  
Nasim Shokouhi ◽  
Sara Saeedi ◽  
Soheila Sarmadi ◽  
Behnaz Moradi ◽  
Elham Feizabad

Abstract Background: Primary carcinoma of fallopian tube is a rare but deadly gynecologic cancer, In addition, its preoperative diagnosis is strict due to the lack of specific symptoms and signs and in most patients, it is an intraoperative finding.Case presentation: A 55-year-old patient, G3Ab1P2 referred to urogynecology clinic of our hospital with chief complaint about heavy, prolonged menstrual bleeding and a permanently abnormal yellow discharge that could not be distinguished from its urinary or vaginal source.After complete diagnostic work-up, the patient became a candidate for hysterectomy due to the drug (Megestrol Acetate) -resistant abnormal vaginal bleeding, her abnormal vaginal bleeding, positive family history of malignancy, and abnormal vaginal discharge.Laparotomy revealed unusual left fallopian tube feature (Large, bulky, and vegetative feature), suspected to malignancy. Intraoperative frozen-section analysis of the left fallopian tube and ovary specimens detected the mass as a high-grade serous carcinoma of fallopian tube. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, and partial omentectomy were performed. The definitive histopathological diagnosis was high-grade serous carcinoma of the left fallopian tube stage 2b with omental involvement without any evidence of lymph-vascular invasion.Conclusions: High-grade serous carcinoma of fallopian tube is likely to present nonspecific symptoms, which may cause considerable delay in diagnosis and treatment. This consequently, affects the prognosis and survival of the patient.


2016 ◽  
Vol 469 (3) ◽  
pp. 351-356 ◽  
Author(s):  
Chang-Tsu Yuan ◽  
Ming-Chieh Lin ◽  
Kuang-Ting Kuo ◽  
Tsung-Hsi Wang ◽  
Tsui-Lien Mao

2009 ◽  
Vol 48 (4) ◽  
pp. 216-219 ◽  
Author(s):  
Rie GOCHO ◽  
Emiko NAKAMURA ◽  
Kyoichi MIYAGAWA ◽  
Jun KANEMOTO ◽  
Toshio SHIMIZU ◽  
...  

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