scholarly journals Genotype Diversity of Newcastle Disease Virus in Nigeria: Disease Control Challenges and Future Outlook

2018 ◽  
Vol 2018 ◽  
pp. 1-17 ◽  
Author(s):  
Muhammad Bashir Bello ◽  
Khatijah Mohd Yusoff ◽  
Aini Ideris ◽  
Mohd Hair-Bejo ◽  
Ben P. H. Peeters ◽  
...  

Newcastle disease (ND) is one of the most important avian diseases with considerable threat to the productivity of poultry all over the world. The disease is associated with severe respiratory, gastrointestinal, and neurological lesions in chicken leading to high mortality and several other production related losses. The aetiology of the disease is an avian paramyxovirus type-1 or Newcastle disease virus (NDV), whose isolates are serologically grouped into a single serotype but genetically classified into a total of 19 genotypes, owing to the continuous emergence and evolution of the virus. In Nigeria, molecular characterization of NDV is generally very scanty and majorly focuses on the amplification of the partial F gene for genotype assignment. However, with the introduction of the most objective NDV genotyping criteria which utilize complete fusion protein coding sequences in phylogenetic taxonomy, the enormous genetic diversity of the virus in Nigeria became very conspicuous. In this review, we examine the current ecological distribution of various NDV genotypes in Nigeria based on the available complete fusion protein nucleotide sequences (1662 bp) in the NCBI database. We then discuss the challenges of ND control as a result of the wide genetic distance between the currently circulating NDV isolates and the commonest vaccines used to combat the disease in the country. Finally, we suggest future directions in the war against the economically devastating ND in Nigeria.

2018 ◽  
Vol 11 (7) ◽  
pp. 930-938 ◽  
Author(s):  
Karim M. Selim ◽  
Abdullah Selim ◽  
Abdelsatar Arafa ◽  
Hussein A. Hussein ◽  
Ahmed A. Elsanousi

Author(s):  
C. Abolnik ◽  
G. H. Gerders ◽  
J. Kitching ◽  
S. Swanepoel ◽  
M. Romito ◽  
...  

Pigeon paramyxovirus type 1 (PPMV-1), a variant of Newcastle disease virus that primarily affects doves and pigeons has been isolated in South Africa since the mid-1980s. Phylogenetic evidence indicates that pigeon paramyxovirus type 1 viruses were introduced in to South Africa on multiple occasions, based on the presence of two separate lineages, 4bi and 4bii, that have been circulating in Europe and the Far East since the early 1990s. During 2006, a PPMV-1 virus was isolated from an African ground hornbil(l Bucorvus leadbeateri) which becamea cutely infected with PPMV-1 and died, probably after scavenging off infected dove carcasses in the region, since a closely-related PPMV-1 strain was also isolated from doves collected nearby. The hornbill isolate had lCPl and MDT values characteristic of PPMV-1s trains. The threat of PPMV-1 to poultry production and biodiversity in southern Africa highlights the importance of monitoring the spread of this strain.


2016 ◽  
Vol 21 (1) ◽  
pp. 235-248
Author(s):  
Amani Saleh ◽  
Rola Ali ◽  
Mohamed Fawzy ◽  
Mokhtar Eltarabily

2017 ◽  
Vol 162 (10) ◽  
pp. 3069-3079 ◽  
Author(s):  
Ahmed Orabi ◽  
Ashraf Hussein ◽  
Ayman A. Saleh ◽  
Mohammed Abu El-Magd ◽  
Muhammad Munir

2008 ◽  
Vol 52 (1) ◽  
pp. 150-155 ◽  
Author(s):  
Hualei Liu ◽  
Zhiliang Wang ◽  
Yongkun Wang ◽  
Chengying Sun ◽  
Dongxia Zheng ◽  
...  

2020 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Safaa A. A. Abdel-Latif ◽  
Asmaa Atef ◽  
Ahmed M. A. Abdel-Aleem ◽  
AL-Hussien M. Dahshan ◽  
Ahmed Ali

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