scholarly journals Screen for human single chain variable region in antibody against human hepatitis C virus core protein binding protein 6

2003 ◽  
Vol 11 (4) ◽  
pp. 389-393
Author(s):  
Yan-Wei Zhong ◽  
Jun Cheng ◽  
Zhong-Dong Zhang ◽  
Min Sun ◽  
Qiang Li ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Protein Binding ◽  
Core Protein ◽  
Binding Protein ◽  
Variable Region ◽  
Single Chain ◽  
Virus Core ◽  
Human Hepatitis

scholarly journals Up-regulating effect of human hepatitis C virus core protein-binding protein 6 on NACA gene promoter

2003 ◽  
Vol 11 (7) ◽  
pp. 959-962 ◽  
Author(s):  
Qian Yang ◽  
Yan Liu ◽  
Jun Cheng ◽  
Ke Li ◽  
Jian-Jun Wang ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Protein Binding ◽  
Core Protein ◽  
Binding Protein ◽  
Gene Promoter ◽  
Virus Core ◽  
Human Hepatitis

Hepatitis C virus core protein interacts with p53-binding protein, 53BP2/Bbp/ASPP2, and inhibits p53-mediated apoptosis

2004 ◽  
Vol 315 (4) ◽  
pp. 788-795 ◽  
Author(s):  
Yongheng Cao ◽  
Tomio Hamada ◽  
Tadashi Matsui ◽  
Takayasu Date ◽  
Kuniyoshi Iwabuchi
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Core Protein ◽  
Binding Protein ◽  
Virus Core

scholarly journals Hepatitis C virus core protein binding to lipid membranes: the role of domains 1 and 2

2008 ◽  
Vol 15 (5) ◽  
pp. 346-356 ◽  
Author(s):  
A. J. Pérez-Berná ◽  
A. S. Veiga ◽  
M. A. R. B. Castanho ◽  
J. Villalaín
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Protein Binding ◽  
Lipid Membranes ◽  
Core Protein ◽  
Virus Core

Expression of hepatitis C virus core protein as a fusion protein with maltose binding protein

1993 ◽  
Vol 38 (4) ◽  
pp. 626-630 ◽  
Author(s):  
Osamu Yokosuka ◽  
Yoshimi Ito ◽  
Jun Sakuma ◽  
Fumio Imazeki ◽  
Masao Ohto ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Fusion Protein ◽  
Core Protein ◽  
Binding Protein ◽  
Maltose Binding Protein ◽  
Virus Core

scholarly journals Specific targeting of hepatitis C virus core protein by an intracellular single-chain antibody of human origin

Hepatology ◽  
2008 ◽  
Vol 48 (3) ◽  
pp. 702-712 ◽  
Author(s):  
Juliane Karthe ◽  
Kathi Tessmann ◽  
Jisu Li ◽  
Raiki Machida ◽  
Maaike Daleman ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Core Protein ◽  
Human Origin ◽  
Single Chain ◽  
Single Chain Antibody ◽  
Specific Targeting ◽  
Virus Core

scholarly journals Clonning, Expression and Identification by Immunohistochemistry of Humanized Single-Chain Variable Fragment Antibody against Hepatitis C Virus Core Protein

2011 ◽  
Vol 60 (1) ◽  
pp. 13-17 ◽  
Author(s):  
YONG-ZHI LUN ◽  
JUN CHENG ◽  
YAN-WEI ZHONG ◽  
ZENG-GUO YU ◽  
QI WANG ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Core Protein ◽  
Microtiter Plate ◽  
Single Chain Variable Fragment ◽  
Antibody Library ◽  
Single Chain ◽  
Virus Core ◽  
Phage Antibody Library ◽  
Healthy Persons

Expression of single-chain variable fragment (scFv) antibodies on the surface of bacteriophage is widely used to prepare antibodies with pre-defined specificities. A phage antibody library containing the gene for scFv antibody against Hepatitis C virus core protein was panned with core protein immobilized on microtiter plate wells. After five rounds of panning 60 phage clones specific to core protein were obtained and one selected clone was sequenced. It was found that the specifically detected antigen consists of 774bp and is capable of encoding 257 amino acids in the patients but not in healthy persons.

Identification of a novel protein binding to hepatitis C virus core protein

2009 ◽  
Vol 24 (7) ◽  
pp. 1300-1304 ◽  
Author(s):  
Yun-ru Chen ◽  
Tian-yan Chen ◽  
Shu-lin Zhang ◽  
Shu-mei Lin ◽  
Ying-ren Zhao ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Protein Binding ◽  
Core Protein ◽  
Virus Core ◽  
Novel Protein

Biosynthesis and biochemical properties of the hepatitis C virus core protein.

1994 ◽  
Vol 68 (6) ◽  
pp. 3631-3641 ◽  
Author(s):  
E Santolini ◽  
G Migliaccio ◽  
N La Monica
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Core Protein ◽  
Biochemical Properties ◽  
Virus Core
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